Introduction & Objectives Meniscal injuries occur approximately 66 to 70 per 100,000 individuals annually (Fig. 1), potentially leading to the development of osteoarthritis (OA) or other degenerative cartilage disease in 10 to 20 years. One of the conventional treatments is meniscal allograft transplantation. However, its limitations constrain its comprehensive application in the healthcare system.
Introduction: Musculoskeletal injuries, widespread across all ages, genders, and sociodemographic groups1, are prevalent in the knee joint. Besides the conservative treatments and physiotherapy, several degenerative and traumatic knee injuries require surgical intervention2. To address one of the most significant challenges in surgical orthopaedic procedures, long-term implant fixation3, an innovative solution ...
Significant progress has been made in tissue engineering (TE), aiming at providing personalized solutions and overcoming the current limitations of traditional tissue and organ transplantation. 3D bioprinting has emerged as a transformative technology in the field, able to mimic key properties of the natural architecture of the native tissues. However, most successes in the area are still limited to avascular o...
Musculoskeletal injuries, widespread across all ages, genders and sociodemographic groups, are prevalent in the knee joint and require a range of treatments - from conservative methods to surgical interventions, such as meniscal resection, repair, reconstruction or tissue engineering (TE) approaches. To address one of the most significant challenges in orthopedic procedures – long-term implant fixation – an inn...
3D bioprinting is a powerful enabling technology for the automated fabrication of biomimetic constructs for skin modelling and repair with high resolution and reproducibility. Bioinks, which often comprise the combination of cells and printable biomaterials, are essential for bioprinting 3D cell-laden constructs emulating the architecture, composition and function of native skin. Tissue- and organ-specific dece...