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Plasma osteopontin is a biomarker for the severity of alcoholic liver cirrhosis...

Simão, Adélia; Madaleno, João; Silva, Nuno; Rodrigues, Fernando; Caseiro, Paula; Costa, José Nascimento; Carvalho, Armando

Background: Implementation of surveillance programs for at-risk populations and identification of biomarkers for early hepatocellular carcinoma (HCC) detection are a major public health goal. Recently, osteopontin (OPN) has attracted attention as a promising biomarker, with some potential advantages compared to alpha-fetoprotein (AFP), but its role in the context of alcoholic cirrhosis has never been assessed. ...


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