119 documents found, page 1 of 12

Neutrophile to lymphocyte and platelet to lymphocyte ratios predict clinical re...

Objective: We aim to study association between neutrophile to lymphocyte (NLR) and platelet to lymphocyte (PLR) ratios and disease activity, and their value to predict bDMARD response. Methods: A set of spondylarthritis (SpA) patients under bDMARD registered in the Reuma.pt registry was studied. Sociodemographic, clinical and laboratorial variables were assessed on bDMARD initiation, 6, 12, 18 and 24 months (M)...

Wunderlich syndrome as a rare complication of polyarteritis nodosa: a case report

Spontaneous subcapsular and perirenal hemorrhage, known as Wunderlich syndrome (WS), is a rare clinical manifestation of polyarteritis nodosa (PAN). We report a case of a 48-year-old male with a history of recurrent episodes of leg muscle tenderness and dysesthesia, bilateral flank pain, painful nodular skin lesions in the lower limbs, weight loss, and difficult-to-control arterial hypertension. The abdominopel...

The benefit of macrolide therapy in patients with pneumococcal pneumonia is onl...

The benefit of macrolide therapy in patients with pneumococcal pneumonia is onl...

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio are not predict...

Pathological complete response (pCR) to neoadjuvant chemotherapy (NAChT) has been validated as a predictor of long-term survival in breast cancer (BC), especially in triple-negative breast cancer (TNBC)

Immune-mediated skin lesions related to biological disease-modifying antirheuma...

Biological disease-modifying antirheumatic drugs (bDMARDs) have revolutionized the treatment of chronic inflammatory rheumatic diseases. However, the physician and the patient should be aware of possible adverse reactions. Skin is one of the most frequent organs involved in bDMARD adverse reactions and immune-mediated skin lesions (IMSL) have rarely been described before in cohort studies and their incidence is...

Adalimumab and number of previous biological disease-modifying antirheumatic dr...

Treatment of inflammatory rheumatic diseases has dramatically changed with the introduction of biologic disease modifying anti-rheumatic drugs (bDMARDs). However, these drugs aren’t exempt from risks and skin lesions are the most frequent adverse reactions. Among the possible adverse skin reactions, immune-mediated skin lesions (IMSL) may occur. Risk factors associated with the occurrence of IMSL in rheumatic p...

Powered smart textile-based exoskeleton for human support movement

Industrial environments require people’s physical efforts related to excessive force, poor posture, and repetitive tasks that increase the risk of developing musculoskeletal diseases. Due to the high prevalence of postural complaints and consequent global health burdens, a significant demand has been conducted to build and implement powered lower and upper limb devices for human enhancement, considering the wor...

Guia dos peixes de água doce e migradores de Portugal Continental

Num total de cerca de 35 500 espécies de peixes conhecidas em todo o mundo, aproxima- damente 18 000 espécies habitam ecossistemas de água doce. Apesar de representarem menos de 1% da superfície terrestre, os ecossistemas de água doce possuem uma enorme diversidade de condições tipicamente instáveis que, associadas ao isolamento geográfico das bacias hidrográficas, favorecem a formação de novas espécies

Determinants of consumers’ frugal innovation acceptance in a developed country

Purpose – This study aims to understand why young people are interested in buying frugal innovations. Design/methodology/approach – Data were collected with a survey administered to 534 university students enrolled in various fields of study (e.g. sciences, technology, economics and fine arts). Using the Tata Nano car as an example of frugal innovation, a model based on the unified theory of acceptance and use ...