9 documents found, page 1 of 1
Etiology and severity of diarrheal diseases in infants at the semiarid region o...
Lima, Aldo A. M.; Oliveira, Domingos B.; Quetz, Josiane S.; Havt, Alexandre; Prata, Mara M. G.; Lima, Ila F. N.; Soares, Alberto M.; Q. Filho, JoséBackground Diarrheal diseases are an important cause of morbidity and mortality among children in developing countries. We aimed to study the etiology and severity of diarrhea in children living in the low-income semiarid region of Brazil. Methodology This is a cross-sectional, age-matched case-control study of diarrhea in children aged 2–36 months from six cities in Brazil’s semiarid region. Clinical, epidemio...
Morbidity, mortality, and long-term consequences associated with diarrhoea from...
Khalil, Ibrahim A.; Troeger, Christopher; Rao, Puja C.; Blacker, Brigette F.; Brown, Alexandria; Brewer, Thomas G.; Colombara, Danny V.Background The protozoan Cryptosporidium is a leading cause of diarrhoea morbidity and mortality in children younger than 5 years. However , the true global burden of C ryptosporidium infection in children younger than 5 years might have been underestimated in previous quantifications because it only took account of the acute eects of diarrhoea. W e aimed to demonstrate whether there is a causal relation betwee...
Epidemiology of enteroaggregative Escherichia coli infections and associated ou...
Rogawski, Elizabeth T.; Guerrant, Richard L.; Havt, Alexandre; Lima, Ila F. N.; Medeiros, Pedro H. Q. S.; Seidman, Jessica C.; McCormick, Benjamin J. J.Background Enteroaggregative E. coli (EAEC) have been associated with mildly inflammatory diarrhea in outbreaks and in travelers and have been increasingly recognized as enteric pathogens in young children with and without overt diarrhea. We examined the risk factors for EAEC infections and their associations with environmental enteropathy biomarkers and growth outcomes over the first two years of life in eight...
Use of antibiotics in children younger than two years in eight countries : a pr...
Rogawski, Elizabeth T.; Platts-Mills, James A.; Seidman, Jessica C.; John, Sushil; Mahfuz, Mustafa; Ulak, Manjeswori; Shrestha, Sanjaya K.Objective To describe the frequency and factors associated with antibiotic use in early childhood, and estimate the proportion of diarrhoea and respiratory illnesses episodes treated with antibiotics. Methods Between 2009 and 2014, we followed 2134 children from eight sites in Bangladesh, Brazil, India, Nepal, Pakistan, Peru, South Africa and the United Republic of Tanzania, enrolled in the MAL-ED birth cohort ...
Apolipoprotein E plays a key role against cryptosporidial infection in transgen...
Azevedo, Orleâncio G. R.; Bolick, David T.; Roche, James K.; Pinkerton, Relana F.; Lima, Aldo A. M.; Vitek, Michael P.; Warren, Cirle A.Apolipoliprotein E (apoE), a critical targeting protein in lipid homeostasis, has been found to have immunoinflammatory effects on murine models of infection and malnutrition. The effects of apoE in undernourished and Cryptosporidium parvuminfected mice have not been investigated. In order to study the role of apoE in a model of C. parvum infection, we used the following C57BL6J mouse genetic strains: APOE-defi...
Effects of glutamine alone or in combination with zinc and vitamin A on growth,...
Lima, Aldo A. M.; Anstead, Gregory M.; Zhang, Qiong; Figueiredo, Ìtalo L.; Soares, Alberto M.; Mota, Rosa M. S.; Lima, Noélia L.; Guerrant, Richard L.OBJECTIVE: To determine the impact of supplemental zinc, vitamin A, and glutamine alone or in combination on growth, intestinal barrier function, stress and satiety-related hormones among Brazilian shantytown children with low median height-for-age z-scores. METHODS: A randomized, double-blind, placebo-controlled trial was conducted in children aged two months to nine years from the urban shanty compound commun...
Zinc, vitamin A, and glutamine supplementation in Brazilian shantytown children...
Lima, Aldo A. M.; Kvalsund, Michelle P.; Souza, Paula P. E. de; Figueiredo, Ítalo L; Soares, Alberto M.; Mota, Rosa M. S.; Lima, Noélia L.OBJECTIVE: To identify the impact of supplemental zinc, vitamin A, and glutamine, alone or in combination, on long-term cognitive outcomes among Brazilian shantytown children with low median height-for-age z-scores. METHODS: A randomized, double-blind, placebo-controlled trial was conducted in children aged three months to nine years old from the urban shanty compound community of Fortaleza, Brazil. Demographic...
Role of NMDA receptors in the trigeminal pathway, and the modulatory effect of ...
Cavalcante, André L. C.; Siqueira, Rafaelly M. P.; Araujo, Joana C. B.; Gondim, Delane V.; Quetz, Josiane S.; Havt, Alexandre; Lima, Aldo A. M.Temporomandibular joint (TMJ) arthritis is a common cause of orofacial pain. In the present study, the modulatory effects of N-methyl-D-aspartate receptors (NMDA-Rs) and magnesium were investigated in TMJ arthritis hypernociception. Male Wistar rats received an intra-articular injection of carrageenan (Cg) in the TMJ, and mechanical hypernociception was measured. The NMDA-R antagonist, MK-801, and magnesium chl...
Zinc, vitamin A, and glutamine supplementation in Brazilian shantytown children...
Lima, Aldo A. M.; Kvalsund, Michelle P.; Souza, Paula P. E. de; Figueiredo, Ítalo L; Soares, Alberto M.; Mota, Rosa M. S.; Lima, Noélia L.OBJECTIVE: To identify the impact of supplemental zinc, vitamin A, and glutamine, alone or in combination, on long-term cognitive outcomes among Brazilian shantytown children with low median height-for-age z-scores. METHODS: A randomized, double-blind, placebo-controlled trial was conducted in children aged three months to nine years old from the urban shanty compound community of Fortaleza, Brazil. Demographic...