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NiTi laser textured implants with improved in vivo osseointegration: an experim...

Costa, M. M.; Miranda, Alice Augusta Macedo; Bartolomeu, Flávio; Carvalho, Óscar Samuel Novais; Matos, S.; Miranda, G.; Silva, Filipe Samuel

Laser surface texturing is a versatile approach for manufacturing implants with suitable surfaces for os-seointegration. This work explores the use of laser to fabricate NiTi textured implants, testing two dif-ferent groove-based designs. Their performance was evaluated in vivo through implantation in Sprague Dawley rats' femur, being then analyzed after 4 and 12 weeks of implantation. Push-out experiments and ...


Multi-material cellular structured orthopedic implants design: in vitro and bio...

Costa, M. M.; Lima, R.; Alves, N.; Silva, N. A.; Gasik, M.; Silva, F. S.; Bartolomeu, F.; Miranda, Georgina

In this study, Selective Laser Melting (SLM) was used to produce mono-material Ti64Al4V- and NiTi-cubic cellular structures with an open-cell size and wall thickness of 500 μm and 100 μm, respectively. Bioactive beta-tricalcium phosphate (βTCP) and polymer poly-ether-ether ketone (PEEK) were used to fill the produced structures open-cells, thus creating multi-material components. These structures were character...


Multi-material NiTi-PEEK hybrid cellular structures by selective laser melting ...

Costa, M. M.; Bartolomeu, Flávio; Palmeiro, J.; Guimarães, B.; Alves, N.; Miranda, G.; Silva, F. S.

In this study, a multi-material NiTi-PEEK cellular structured solution was designed, produced and characterized targeting orthopedic applications. For that purpose, Selective Laser Melting (SLM) technique was used to produce NiTi cellular structures with different open-cell sizes and wall thicknesses. Hot Pressing (HP) technique was used to introduce PEEK in the open-cells of NiTi structures to obtain multi-mat...


Engineering the elastic modulus of NiTi cellular structures fabricated by selec...

Bartolomeu, Flávio; Costa, M. M.; Alves, N.; Miranda, G.; Silva, Filipe Samuel

Nickel-titanium (NiTi) cellular structures are a very promising solution to some issues related to orthopaedic implant failure. These structures can be designed and fabricated to simultaneously address a combination of mechanical and physical properties, such as elastic modulus, porosity, wear and corrosion resistance, biocompatibility and appropriate biological environment. This ability can enhance the modest ...


Additive manufacturing of NiTi-Ti6Al4V multi-material cellular structures targe...

Bartolomeu, Flávio; Costa, M. M.; Alves, N.; Miranda, G.; Silva, Filipe Samuel

The amount of hip revision surgeries is significantly increasing due to the loss of fixation between implant and bone, that leads to implant failure. The stiffness mismatch between Ti6Al4V hip implants and bone tissue, the non-uniform implant-bone contact pressure, and the poor wear resistance of Ti6Al4V are pointed as three critical issues that contribute to these implant's failure. In this study, a multi-mate...



Development of β-TCP-Ti6Al4V structures: driving cellular response by modulatin...

Costa, M. M.; Lima, Rui Augusto Ribeiro; Fonseca, Francisca Rocha Melo; Bartolomeu, Flávio; Alves, N.; Miranda, Alice Augusta Macedo; Gasik, M.

Load-bearing implants success is strongly dependent on several physical and chemical properties that are known to drive cellular response. In this work, multi-material β-TCP-Ti6Al4V cellular structures were designed to combine Ti6Al4V mechanical properties and β-Tricalcium Phosphate bioactivity, in order to promote bone ingrowth as the bioactive material is being absorbed and replaced by newly formed bone. In t...


Implant surface design for improved implant stability - a study on Ti6Al4V dens...

Bartolomeu, Flávio; Costa, M. M.; Gomes, J. R.; Alves, N.; Abreu, C. S.; Silva, Filipe Samuel; Miranda, Maria Georgina Macedo

Focusing on implant surface design, aiming to improve implant primary stability, SLM technology was explored to produce dense and cellular structured Ti6Al4V specimens. The SLM specimens and also a commercial casted/forged Ti6Al4V group, were sandblasted and acid-etched to obtain a moderate surface roughness topography, typically used in implant manufacturing. Ti6Al4V-bone interaction and tribological performan...


45S5 BAG-Ti6A14V structures: The influence of the design on some of the physica...

Fonseca, Francisca Rocha Melo; Lima, R.; Costa, M. M.; Bartolomeu, F.; Alves, N. M. Fernandes; Miranda, Alice Augusta Macedo; Gasik, M.

Multi-material Ti6Al4V cellular structures impregnated with 45S5 bioactive glass were designed and produced using Selective Laser Melting (SLM), an additive manufacturing technique, combined with Press and Sintering focusing on load bearing components like hip implants. These structures were designed to combine Ti6Al4V mechanical properties and promote bone ingrowth into the structure as the bioactive material ...


Effect of HAp and beta-TCP incorporation on the tribological response of Ti6Al4...

Dantas, T. A.; Costa, M. M.; Miranda, Maria Georgina Macedo; Silva, Filipe Samuel; Abreu, C. S.; Gomes, J. R.

Titanium and its alloys have been widely used in many engineering areas due to their properties. Despite having a high implant-tissue osseointegration time, Ti6Al4V has been extensively used in prosthesis and articular implants. To promote a faster bone ingrowth and consequently reduce the implant fixation time, the addition of a bioactive phase to form a biocomposite seems to be an excellent solution. Because ...


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