2 documents found, page 1 of 1
Sustained drug release by contact lenses for glaucoma treatment - a review
Carvalho, I.M.; Marques, C.S.; Oliveira, Rita; Barata, Pedro; Costa, P.C.; Ferreira, D.C.In the context of ocular pharmacology, there is a growing need for innovative delivery platforms for a convenient and sustained drug release into the eye, especially for chronic diseases that require the adoption of a strict insurmountable treatment regimen for a large part of the affected population, as in the case of glaucoma. Due to the large residence time of the contact lenses in the eye, its use for susta...
Protective effect of C. sativa leaf extract against UV mediated-DNA damage in a...
Almeida, Isabel F.; Pinto, A.S.; Monteiro, C.; Monteiro, H.; Belo, L.; Fernandes, J.; Bento, A.R.; Duarte, T.L.; Garrido, J.; Bahia, Maria FernandaToxic effects of ultraviolet (UV) radiation on skin include protein and lipid oxidation, and DNA damage. The latter is known to play a major role in photocarcinogenesis and photoaging. Many plant extracts and natural compounds are emerging as photoprotective agents. Castanea sativa leaf extract is able to scavenge several reactive species that have been associated to UV-induced oxidative stress. The aim of this...