Introduction: Mental health warrants exist in most countries and are issued when patients have severe mental illness, refuse treatment, and present a serious risk to themselves or others. We describe the epidemiology of mental health warrant requests received, and warrants issued by a Public Health Unit in a Portuguese region, as well as subsequent hospital admissions before and during the COVID-19 pandemic.Met...
Models-at different levels of abstraction and pertaining to different engineering views-are central in the design of railway networks, in particular signalling systems. The design of such systems must follow numerous strict rules, which may vary from project to project and require information from different views. This renders manual verification of railway networks costly and error-prone. This paper presents E...
A população LGBTI, composta por lésbicas, gays, bissexuais e, em especial, as travestis, homens e mulheres transexuais (Trans) e intersexo enfrentam barreiras no acesso aos bens e serviços de saúde, associadas ao preconceito e discriminação. Sabe-se que a saúde bucal está intimamente relacionada com os fatores sistêmicos como, por exemplo, alterações hormonais. O tratamento odontológico em pessoas trans configu...
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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2016.; Da perspectiva do sistema elétrico de energia, o conceito de geração distribuída (GD) pode ser claramente dividido em duas categorias: de pequena e de grande escala. Atualmente, há grande dedicação em estudos de integração da GD de grande escala ao redor do...
The synthesis of galacto-oligosaccharides (GOS) by the action of Aspergillus oryzae b-galactosidase free and immobilized on magnetic polysiloxane-polyvinyl alcohol (mPOS-PVA) was studied. A maximum GOS concentration of 26% (w/v) of total sugars was achieved at near 55% lactose conversion from 50%, w/v lactose solution at pH 4.5 and 40 C. Trisaccharides accounted for more than 81% of the total GOS produced. GOS ...
Type 2 topoisomerases, in particular the A isoform in human cells, play a key role in cohesion and sister chromatid separation during mitosis. These enzymes are thus vital for cycling cells and are obvious targets in cancer chemotherapy. Evidence obtained in yeast and Xenopus model systems indicates that conjugation of topoisomerase 2 with small ubiquitin-like modifier (SUMO) proteins is required for its mitoti...
β-Galactosidase from Aspergillus oryzae is an enzyme with a wide industrial application, mostly in the hydrolysis of lactose and, more recently, in the synthesis of oligosaccharides. Several advantages are associated with the application of immobilized enzymes on magnetic supports. In this work, β-galactosidase was covalently immobilised onto a Polysiloxane-Polyvinyl Alcohol Magnetic Composite (mPOS-PVA), Magne...