5 documents found, page 1 of 1
Chitosan-Based Membranes for Skin Wound Repair in a Dorsal Fold Chamber Rat Model
Casimiro, Maria Helena; Ferreira, Luís M.; Santos, Pedro M. P.; Leal, João P.; Rodrigues, Gabriela; Iria, Inês; Alves, Sara; Pais, Diogo; Casal, DiogoFrequently, deep partial and full-thickness skin wounds do not spontaneously regenerate. To restore the normal function of skin, epidermal and dermal components have to be supplied to the wound bed by grafting various substrates. Available options are limited and frequently costly. Herein, authors present a possible approach using 3D skin scaffolds capable of mimicking structure and biological functions of the ...
Multifunctionality of the [C2mim][Ln(fod)4] series (Ln = Nd-Tm except Pm): magn...
Cerdeira, Ana C.; Leal, João P.; Avó, João; Viola, Catarina; Casimiro, Maria H.; Ferreira, Luis M.; Almeida Paz, Filipe A.; Pereira, Laura C. J.A series of nine tetrakis lanthanide β-diketonate complexes of the type [C2mim][Ln(fod)4] (C2mim = 1-ethyl-3-methylimidazolium, fod = 6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedionate) were prepared, with yields above 80%, and their thermochemical, photophysical and magnetic susceptibilities were evaluated. Thermochemical studies presented a rare and reversible conversion between two solid phases (polymo...
Chitosan/PVA Based Membranes Processed by Gamma Radiation as Scaffolding Materi...
Casimiro, Maria Helena; Pereira, Andreia; Leal, João P.; Rodrigues, Gabriela; Ferreira, Luís M.Some of the current strategies for the development of scaffolding materials capable of inducing tissue regeneration have been based on the use of polymeric biomaterials. Chitosan, in particular, due to its recognized biological activity has been used in a number of biomedical applications. Aiming the development of chitosan-based membranes with improved cell adhesion and growth properties to be used as skin sca...
Automated Identification and Classification of Stereochemistry: Chirality and D...
Leal, João P.; Falcao, Andre O.; Teixeira, Ana L.Stereoisomers have the same molecular formula and the same atom connectivity and their existence can be related to the presence of different three-dimensional (3D) arrangements. Stereoisomerism is of great importance in many different fields since the molecular properties and biological effects of the stereoisomers are often significantly different. Most drugs for example, are often composed of a single stereoi...
ThermInfo: Collecting, Retrieving, and Estimating Reliable Thermochemical Data
Teixeira, Ana L.; Santos, Rui C.; Leal, João P.; Martinho Simões, José A.; Falcao, Andre OStandard enthalpies of formation are used for assessing the efficiency and safety of chemical processes in the chemical industry. However, the number of compounds for which the enthalpies of formation are available is many orders of magnitude smaller than the number of known compounds. Thermochemical data prediction methods are therefore clearly needed. Several commercial and free chemical databases are current...