4 documents found, page 1 of 1
Evaluation of partial thromboplastin time, thrombin time and prothrombin time o...
Miranda, Vanessa Maria Andrade Machado; Barbosa Filho, José Pedro Martins; Costa, Romero Marcos Pedrosa Brandão; Leite, Ana Cristina LimaFibrinolytic proteases are enzymes that degrade the fibrin, a main component of the blood clot. Thus, the present study aimed to understand the evaluation of aPTT, TT and PT on plasma treated with a fibrinolytic protease produced by Mucor subtillissimus. To assess the anticoagulant effect, the protease was used in different concentrations of 0.5-2.5mg/mL. The tests showed that the enzyme promoted a significant ...
Protease with fibrinolytic and collagenolytic activity produced by Aspergillus ...
Cardoso, Kethylen Barbara Barbosa; Nascimento, Thiago Pajeú; Oliveira, Vagne de Melo; Costa, Romero Marcos Pedrosa Brandão; Pastrana, LorenzoProteases play a fundamental role in the economy, being present in several industrial sectors. Among the fungi known to produce proteases, the genus Aspergillus stands out. Thus, the objective of this work was to produce proteases from solid state fermentation of Aspergillus ochraceus, purify, characterize and evaluate their potential in the production of collagenolytic and fibrinolytic enzymes. For this, the t...
Purification of a lectin from Cratylia mollis crude extract seed by a single st...
Nascimento, Cynthia Oliveira; Costa, Romero Marcos Pedrosa Brandão; Soares, Paulo Antônio; Herculano, Polyanna Nunes; Porto, Tatiana SouzaThe partitioning and purification of lectins from the crude extract of Cratylia mollis seeds (Cramoll 1,4) was investigated in aqueous two-phase systems (ATPS). A factorial design model (24) was used to evaluate the influence of polyethylene glycol (PEG) molar mass (15008000g/mol), PEG concentration (12.517.5% w/w), phosphate (1015% w/w) concentration, and pH (68) on the differential partitioning, purification ...
Brazilian kefir-fermented sheep's milk, a source of antimicrobial and antioxida...
de Lima, Meire dos Santos Falcão; da Silva, Roberto Afonso; da Silva, Milena Fernandes; da Silva, Paulo Alberto BezerraFermented milks are a source of bioactive peptides and may be considered as functional foods. Among these, sheep's milk fermented with kefir has not been widely studied and its most relevant properties need to be more thoroughly characterized. This research study is set out to investigate and evaluate the antioxidant and antimicrobial properties of peptides from fermented sheep's milk in Brazil when produced by...