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Group B Streptococcus rectovaginal colonization screening on term pregnancies: ...

Costa, SC; Machado, AP; Teixeira, C; Cerqueira, L; Rodrigues, T; Ribeiro, M; Moucho, M

Objectives The aim of this study was to evaluate if screening Group B Streptococcus colonization by intrapartum polymerase chain reaction could improve intrapartum administration of antibiotic prophylaxis, compared with antepartum culture screening and analyze the sensitivity and specificity of polymerase chain reaction test. Methods 198 pregnant women with Group B Streptococcus colonization antepartum culture ...

Date: 2023   |   Origin: Repositório Aberto da Universidade do Porto
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The cdh1 c.1901c>t variant: A founder variant in the portuguese population w...

Barbosa-Matos, R; Leal Silva, R; Garrido, L; Aguiar, AC; Garcia-Pelaez, J; André, A; Seixas, S; Sousa, SP; Ferro, L; Vilarinho, L; Gullo, I; Devezas, V

Hereditary diffuse gastric cancer (HDGC) caused by CDH1 variants predisposes to early-onset diffuse gastric (DGC) and lobular breast cancer (LBC). In Northern Portugal, the unusually high number of HDGC cases in unrelated families carrying the c.1901C>T variant (formerly known as p.A634V) suggested this as a CDH1-founder variant. We aimed to demonstrate that c.1901C>T is a bona fide truncating variant inducing ...

Date: 2021   |   Origin: Repositório Aberto da Universidade do Porto
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