3 documents found, page 1 of 1
Simultaneous monitoring of CMV and human herpesvirus 6 infections and diseases ...
Costa, Fernanda Aparecida; Soki, Marcelo Naoki; Andrade, Paula Durante; Bonon, Sandra Helena Alves; Thomasini, Ronaldo Luis; Sampaio, Ana MariaOBJECTIVE: The aim of this study was to simultaneously monitoring cytomegalovirus and human herpesvirus 6 active infections using nested-polymerase chain reaction and, together with clinical findings, follow the clinical status of patients undergoing liver transplant. INTRODUCTION: The human β-herpesviruses, including cytomegalovirus and human herpesvirus 6, are ubiquitous among human populations. Active i...
Withdrawal of maintenance therapy for cytomegalovirus retinitis in AIDS patient...
Waib, Luis Fernando; Bonon, Sandra Helena Alves; Salles, Angela Christina; Benard, Gil; Oliveira, Augusto César Penalva de; Pannuti, Claudio SergioBACKGROUND: Before the introduction of highly active antiretroviral therapy (HAART), CMV retinitis was a common complication in patients with advanced HIV disease and the therapy was well established; it consisted of an induction phase to control the infection with ganciclovir, followed by a lifelong maintenance phase to avoid or delay relapses. METHODS: To determine the safety of CMV maintenance therapy withdr...
Comparison of serology, antigenemia assay and the polymerase chain reaction for...
Bonon, Sandra Helena Alves; Rossi, Cláudio Lúcio; Souza, Cármino Antonio de; Vigorito, Afonso Celso; Costa, Sandra Cecília BotelhoForty-six allogeneic hematopoietic stem cell transplantation (HSCT) patients were monitored for the presence of CMV antibodies, CMV-DNA and CMV antigens after transplantation. Immunoenzymatic serological tests were used to detect IgM and the increase in CMV IgG antibodies (increase IgG), a nested polymerase chain reaction (N-PCR) was used to detect CMV-DNA, and an antigenemia assay (AGM) was used to detect CMV ...