19 documents found, page 1 of 2

Electrospun polycaprolactone membranes functionalized with nanochitin for enhan...

The encapsulation of photosensitizers (PSs) in electrospun membranes has emerged as a promising approach in photodynamic therapy (PDT) on tumor sites, overcoming the drawbacks associated with systemic administration. In this work, localized implants for cancer treatment using PDT were developed by incorporating EL-2 squaraine into poly(epsilon-caprolactone) (PCL) electrospun microfibers. The latter were coated ...

Localized cancer photodynamic therapy approach based on core–shell electrospun ...

Photodynamic therapy (PDT) has been considered a promising treatment for several types of cancer, including cervical cancer. Localized drug delivery systems (DDSs) based on nanofibers produced by electrospinning have emerged as a powerful platform to carry and deliver photosensitizers (PSs) onto or adjacent to the tumor site, thereby promoting higher therapeutic efficacy and reducing the side effects to healthy...

The potential of algae as a source of cellulose and its derivatives for biomedi...

Cellulose has been intensively investigated for biomedical applications, because of its excellent properties, like biodegradability, biocompatibility, abundant availability of renewable resources and cost-effectiveness. Among all sources of cellulose, marine macroalgae or seaweeds, are acquiring tremendous attention, due to their high availability around the world. Moreover, the atypical proliferation of some e...

Drug delivery systems for photodynamic therapy: the potentiality and versatilit...

Recently, photodynamic therapy (PDT) has become a promising approach for the treatment of a broad range of diseases, including oncological and infectious diseases. This minimally invasive and localized therapy is based on the production of reactive oxygen species able to destroy cancer cells and inactivate pathogens by combining the use of photosensitizers (PSs), light, and molecular oxygen. To overcome the dra...

Chitosan/nanocellulose electrospun fibers with enhanced antibacterial and antif...

The combination of biodegradable fibers at nanoscale with plant-based extracts is attracting increasing attention to produce wound dressing systems. In this work, nanofibers based on chitosan (CS), poly(ethylene oxide) (PEO), cellulose nanocrystals (CNC) and acacia plant-based extract were developed by electrospinning. Firstly, the polymeric formulations and electrospinning parameters were optimized, resulting ...

Active natural-based films for food packaging applications: the combined effect...

This work aimed to evaluate the potential of chitosan/cellulose nanocrystals (CNC) films to be used as active pads for meat packages to prolong its shelf-life and preserve its properties over time. Several CNC concentrations (5, 10, 25, and 50wt%) were tested and the films were produced by solvent casting. The developed samples were characterized by ATR-FTIR, TGA, FESEM, and XRD. The transparency, antimicrobial...

Development of chitosan-gelatin nanofibers with cellulose nanocrystals for skin...

In this work, natural-based and biodegradable nanofibers were produced by electrospinning for drug delivery and wound dressing applications, using gelatin (Gel), chitosan (CS), cellulose nanocrystals (CNC) and natural propolis extract. The polymeric formulations and electrospinning parameters were optimized, resulting in the development of Gel/CS nanofibers with mean diameters of 97 nm. CNC were successfully in...

Electrospun natural nanofibres with bioactive plant extracts for therapeutic ap...

The purpose of this work was to develop antibacterial biodegradable nanofibers with CS and PEO biopolymers reinforced with cellulose nanocrystals (CNC) by electrospinning. Firstly, CS/PEO nanofibers production was optimized and the effect of different CNC concentrations was investigated. Electrospun nanofibers were characterized by FESEM, FTIR, TGA, XRD and DMA techniques. Finally, a plant-based extract (Acacia...

Bio-based materials for food packaging applications

Smart and sustainable materials for military applications based on natural fibr...

Multifunctional fibrous systems were developed within this research work, giving special importance to the electrical conductivity and antibacterial activity. The functionalization of several natural fibres (jute, sisal, coir, flax and cotton) with silver nanoparticles (Ag NPs) was successfully achieved using a sustainable and eco-friendly method, namely polyethylene glycol (PEG) reduction. FESEM images, GSDR a...