159 documents found, page 1 of 16

Abnormal p53 High-Grade Endometrioid Endometrial Cancer

Publisher Copyright: © 2024 by the authors.; Objective: Our primary objective was to evaluate the oncologic outcomes of patients with abnormal p53 FIGO grade 3 (high-grade) endometrioid endometrial cancer. As secondary objectives, we determined the global prevalence of abnormal p53 in grade 3 endometrioid endometrial carcinomas and the geographical variations. Methods: The following electronic databases were se...

Growth curve models for weight among infants

Publisher Copyright: © 2024 JBI.; Objective: This scoping review aims to provide a systematic overview of the literature on statistical models to estimate weight growth curves among infants, examining key features such as study design, sample size, and statistical approaches. Introduction: Growth models were first developed to estimate individuals’ growth curves by modeling each individual separately. Later, wi...

Exploring depression in adults over a decade

Funding Information: The present publication was funded by Fundac\u0327a\u0303o Cie\u0302ncia e Tecnologia, IP national support, through UID/04923 - Comprehensive Health Research Centre. Publisher Copyright: © The Author(s) 2025.; Depression, as a prevalent global mental health disorder, stands as one of the main causes of disability worldwide, imposing significant individual, societal, and economic burdens. Wh...

Augusto e Jaime Celestino da Costa : personal libraries at NOVA Medical School

Augusto Celestino da Costa, a renowned histologist, and his son Jaime Celestino da Costa, a distinguished surgeon, represent two generations of prominent portuguese physicians. This study examines their personal libraries, which were donated to the Nova Medical School, Universidade Nova de Lisboa, and are now held with restricted access at the institution’s library. Using a mixed-methods analysis that integrate...

Bibliometric analysis of libraries and the 2030 Agenda

The United Nations held a meeting in 2015 where the 2030 Agenda was adopted. This agenda is ambitious and aims to achieve the Sustainable Development Goals across the universe, covering economic, cultural, environmental and social development. The 17 Sustainable Development Goals target several areas of society, including libraries and information science. These institutions provide access to information and su...

Innovative Learning in Undergraduate Medical Teaching: Perspective Based on Thi...

We reviewed an innovative project in undergraduate medical education, which used problem-based learning and concept maps in pathophysiology teaching. We analyzed publications starting in 1995 and until 2024, to identify factors contributing to its continuity and impact, nationally and internationally.Problem-based learning was based on the methodology developed by Howard Barrows, a founder of the method. In 199...

Augusto e Jaime Celestino da Costa

Efficacy of therapeutic interventions for idiopathic recurrent pregnancy loss

Funding Information: The author(s) declare that financial support was received for the research and/or publication of this article. This study in the context of the \u201CWomen\u2019s Health and Maternal Fetal Research Group\u201D was partially co-financed by Hospital da Luz Lisboa under the initiative \u201CLuz Investiga\u00E7\u00E3o.\u201D The sponsor did not have any role in the study design, in the collecti...

The emerging landscape of SGLT2 inhibitors in pediatric populations with kidney...

Sodium-glucose cotransporter 2 inhibitors (SGLT2i), originally developed as innovative antihyperglycemic agents, have demonstrated significant benefits in improving metabolic markers and protecting the kidneys and heart in patients with or without type 2 diabetes mellitus. The mechanisms behind these unexpected cardiorenal benefits cannot be attributed solely to improved glycemic control. Recent data suggest th...

A strategic roadmap for the wine sector in the Setúbal peninsula

The wine sector contributes significantly to economic, environmental and social development. In Portugal, the Setúbal Peninsula is one of the fourteen wine regions. Operated by numerous local businesses in a rural area, the wine industry generates enhanced value and provides jobs in the region. The main purpose of this research is to study the wine sector in the Setúbal Peninsula, Portugal, in the context of th...