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Combination of naltrexone and isotretinoin for the treatment of darier disease
Costa, Tomás; Rebelo, Clarisse; Pinto, Gabriela Marques; Duarte, BrunoDarier disease (DD) is an autosomal-dominant genodermatosis in which mutations in the ATP2A2 gene result in impaired intercellular adhesion and epidermal blistering. Treatment options usually rely on systemic retinoids, but a refractory disease is still a therapeutical challenge. Given the similarity of DD pathogenesis with Hailey-Hailey disease, concomitant treatment with low-dose-naltrexone (LDN) has been pro...
Date: 2023
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Origin: Sapientia - Universidade do Algarve
Isokinetic profile of the shoulder internal and external rotators in surfers
Madeira, Miguel; Nobre, Pedro; Costa, Tomás; Almeida, Vasco; Sousa, João Paulo; Pereira, Ângela Maria
Date: 2018
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Origin: Egas Moniz - Cooperativa de Ensino Superior, CRL