31 documents found, page 1 of 4

Liberdade em palavras: coletânea de poemas

FRAILTY SYNDROME IN INSTITUTIONALIZED OLDER ADULTS: IS HYPERTENSION A PROTECTIV...

Introduction: Portuguese older adults have a high prevalence of chronic disease, such as hypertension. Frailty is a multidimensional syndrome, in which a state of extreme vulnerability to endogenous and exogenous factors is recognized, due to cumulative decline associated with the ageing process, potentially leading to a state of total dependence. The aim of this investigation was to establish na association be...

Internationalization of higher education: beyond international mobility

Internationalisation cannot be thought without accurately understanding the persistent changes the global world is facing, and its utmost purpose must be to improve education and research quality as well as significantly contribute to society. Even with a meaningful number of international, national, regional and local initiatives actively promoting internationalisation through mobility programs, the students i...

Nutrition day em residência geriátrica: determinantes da desnutrição

Internacionalização do ensino superior: para além da mobilidade internacional

A internacionalização não pode ser implementada na ausência do entendimento sobre as mudanças permanentes a que o mundo global está hoje sujeito e o seu propósito deve ser a melhoria da qualidade e dar um contributo significativo para a sociedade. Mesmo na presença de um número considerável de estratégias internacionais, nacionais, regionais e locais que dinamizam a internacionalização através da mobilidade, o ...

Errors in protein synthesis increase the level of saturated fatty acids and aff...

The occurrence of protein synthesis errors (mistranslation) above the typical mean mistranslation level of 10-4 is mostly deleterious to yeast, zebrafish and mammal cells. Previous yeast studies have shown that mistranslation affects fitness and deregulates genes related to lipid metabolism, but there is no experimental proof that such errors alter yeast lipid profiles. We engineered yeast strains to misincorpo...

Guidelines and recommendations on yeast cell death nomenclature

Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cel-lular demise. However, the investigation of yeast cell death is a relatively young field, and a widely accepted set of concepts and terms is still missing. Here, we propose unified criteria for the defi-nition of accide...

Errors in protein synthesis increase the level of saturated fatty acids and aff...

The occurrence of protein synthesis errors (mistranslation) above the typical mean mistranslation level of 10-4 is mostly deleterious to yeast, zebrafish and mammal cells. Previous yeast studies have shown that mistranslation affects fitness and deregulates genes related to lipid metabolism, but there is no experimental proof that such errors alter yeast lipid profiles. We engineered yeast strains to misincorpo...

Production of orotic acid by a Klura3 mutant of Kluyveromyces lactis

We demonstrated that a Klura3, mutant of the yeast Kluyveromyces lactis is able to produce and secrete into the growth medium considerable amounts of orotic acid. Using yeast extractpeptoneglucose (YPD) based media we optimized production conditions in flask and bioreactor cultures. With cells grown in YPD 5% glucose medium, the best production in flask was obtained with a 1:12.5 ratio for flask: culture volume...

A importância do ensino da história militar aos oficiais das Forças Armadas

O objetivo deste trabalho é verificar qual a importância da história militar na formação dos oficiais das Forças Armadas portuguesas. Através de uma consulta à bibliografia existente sobre o assunto, procurámos identificar qual o uso que os oficiais fazem da história militar no desempenho da sua profissão e de que forma este tem reflexo nos currículos da disciplina, nas escolas de formação militar. Numa fase su...