2 documents found, page 1 of 1
Steroids from the Brazilian Zoanthids Palythoa caribaeorum and Palythoa variabilis
Pinto,Francisco C. L.; Almeida,José Gustavo L.; Silveira,Edilberto R.; Costa,Arinice M.; Guimarães,Larissa A.; Wilke,Diego V.; Costa-Lotufo,Letícia V.Two unreported ergostane-type sterols 24(R)-7α-hydroperoxy-ergost-5-en-3β-ol and 6β-carboxyl-24(R)-(8→6)-abeo-ergostan-3β,5β-diol, along with seven known ones were isolated from the hexane and alcohol extracts from the zoanthids Palythoa caribaeorum and Palythoa variabilis. The structures of the new compounds were determined using spectroscopic techniques, including 1D and 2D nuclear magnetic resonance (NMR), h...
Suzuki-Miyaura Coupling between 3-Iodolawsone and Arylboronic Acids. Synthesis ...
Gomes,Sara L. S.; Militão,Gardenia C. G.; Costa,Arinice M.; Pessoa,Cláudia Ó.; Costa-Lotufo,Letícia V.; Cunha-Junior,Edézio F.; Torres-Santos,Eduardo C.A series of 2-hydroxy-3-arylnaphthalene-1,4-diones (3-aryllawsones) were synthesized by Suzuki-Miyaura cross coupling reaction of 3-iodolawsone with arylboronic acids/esters. The hydroxylated resulting products were transformed into their corresponding N,N-diethyl carbamates. The antineoplastic and antileishmanial activities of the compounds were evaluated and compared with lapachol and its carbamate, providing...