2 documents found, page 1 of 1
Detection of Lsr2 gene of Mycobacterium leprae in nasal mucus
Custodio,Luiz Antonio; Saito,Alexandre; Amarante,Marla Karine; Fujita,Thiago Cezar; Perim,Aparecida de Lourdes; Costa,Ivete Conchon; Felipe,IoniceIn the present study, nasal mucus from patients with leprosy were analyzed by PCR using specific primers for Lsr2 gene of Mycobacterium leprae. The presence of Lsr2 gene in the nasal mucus was detected in 25.80% of patients with paucibacillari leprosy, and 23.07% of contacts. Despite the absence of clinical features in the contact individuals, it was possible to detect the presence of Lsr2 gene in the nasal muc...
The effects of nitric oxide on the immune response during giardiasis
Pavanelli,Wander Rogério; Gutierrez,Fredy Roberto Salazar; Silva,Jean Jerley Nogueira da; Costa,Ivete Conchon; Menezes,Maria Claudia Noronha Dutra deNitric oxide (NO) is a free radical synthesized from L-arginine by different isoforms NO-synthases. NO possesses multiple and complex biological functions. NO is an important mediator of homeostasis, and changes in its generation or actions can contribute or not to pathological states. The knowledge of effects of NO has been not only important to our understanding of immune response, but also to new tools for r...