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Evaluation of antifungal activity and potential application as fluorescent prob...

Gomes, Vanessa S. D.; Ferreira, João C. C.; Boto, Renato E.; Almeida, Paulo; Fernandes, José R.; Sousa, Maria João; Reis, Lucinda V.

The antifungal performance and the possible use as fluorescent probes of a series of squarylium dyes derived from indolenine and benzo[e]indole previously synthesized was evaluated. Some photophysical properties were performed in ethanol and phosphate buffer, and the type of aggregates form in phosphate buffer was analyzed. Using the 1,3-diphenylisobenzofuran assay, a qualitative assessment of the capacity of d...


Light-Activated Antimicrobial Surfaces Using Industrial Varnish Formulations to...

Santos, Madson R. E.; Mendonça, Patrícia V.; Branco, Rita; Sousa, Rúben; Dias, Carla; Serra, Arménio C.; Fernandes, José R.; Magalhães, Fernão D.

Evidence has shown that hospital surfaces are one of the major vehicles of nosocomial infections caused by drug-resistant pathogens. Smart surface coatings presenting multiple antimicrobial activity mechanisms have emerged as an advanced approach to safely prevent this type of infection. In this work, industrial waterborne polyurethane varnish formulations containing for the first time cationic polymeric biocid...


Quinoline- and benzoselenazole-derived unsymmetrical squaraine cyanine dyes: de...

Lima, Eurico; Boto, Renato E.; Ferreira, Diana P.; Fernandes, José R.; Almeida, Paulo; Ferreira, Luis F. V.; Souto, Eliana B.; Silva, Amélia M.

Photodynamic therapy is an innovative treatment approach broadly directed towards oncological diseases. Its applicability and efficiency are closely related to the interaction of three main components, namely a photosensitizer, light and molecular triplet oxygen, which should drive cell death. Recently, several studies have demonstrated that squaraine cyanine dyes have a set of photophysical and photochemical p...


Red and near-infrared absorbing dicyanomethylene squaraine cyanine dyes: photop...

Martins, Tiago D.; Lima, Eurico; Boto, Renato E.; Ferreira, Diana Sara Pereira; Fernandes, José R.; Almeida, Paulo; Ferreira, Luis F. V.

Photodynamic therapy is a medical modality developed for the treatment of several diseases of oncological and non-oncological etiology that requires the presence of a photosensitizer, light and molecular oxygen, which combined will trigger physicochemical reactions responsible for reactive oxygen species production. Given the scarcity of photosensitizers that exhibit desirable characteristics for its potential ...


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