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Arbovirus, herpesvirus, and enterovirus associated with neurological syndromes ...

Leon,Lucas Lopes; Lima,Rodrigo Gonçalves de; Boffi,Lídia Cristian; Bindilatti,Raissa Nery; Garlipp,Célia Regina; Costa,Sandra Cecília Botelho

Abstract INTRODUCTION: Herpesviruses, enteroviruses, and arboviruses are important because of their clinical relevance and ability to cause meningitis, encephalitis, meningoencephalitis, and other diseases. The clinical virology associated with diagnostic technologies can reduce the morbidity and mortality of such neurological manifestations. Here we aimed to identify the genomes of agents that cause neurologic...

Date: 2021   |   Origin: Oasisbr

Active human Cytomegalovirus infection and Glycoprotein B genotypes in Brazilia...

Dieamant,Débora de Campos; Bonon,Sandra Helena Alves; Prates,Liliane Cury; Belangelo,Vera Maria Santoro; Pontes,Erika R.; Costa,Sandra Cecília Botelho

A prospective analysis of active Human Cytomegalovirus infection (HCMV) was conducted on 33 pediatric renal or hematopoietic stem cell post-transplant patients. The HCMV-DNA positive samples were evaluated for the prevalence of different gB subtypes and their subsequent correlation with clinical signs. The surveillance of HCMV active infection was based on the monitoring of antigenemia (AGM) and on a nested pol...

Date: 2010   |   Origin: Oasisbr

Neuroinflamatory and immunological changes in frailty syndrome and cytomegalovi...

Caldeira,Marcelo Henrique Reis; Neto,Virginio Rubin; Guariento,Maria Elena; Costa,Sandra Cecília Botelho

<p>There is growing interest in understanding the evolution and possible prevention of frailty, as well as the pathophysiological process of diseases that trigger this syndrome with important functional consequences. Research has shown that chronic latent human cytomegalovirus (HCMV) in the elderly population is highly prevalent in the frail elderly and is an important trigger of limitations. The prevalence of ...

Date: 2010   |   Origin: Oasisbr

Detection of human herpesvirus-7 by qualitative nested-PCR: comparison between ...

Thomasini,Ronaldo Luis; Martins,Juliana de Moraes; Parola,Daniela Corte; Bonon,Sandra Helena Alves; Boin,Ilka de Fátima Santana Ferreira

Diagnosis of human herpesvirus-7 active infection in transplant patients has proved difficult, because this virus is ubiquitous and can cause persistent infections in the host. The significance of viral DNA detected in leukocytes by PCR is unclear and cross-reaction in serological tests may occur. This study aimed to evaluate nested-PCR to detect human herpesvirus-7 active infection in liver transplant recipien...

Date: 2008   |   Origin: Oasisbr

Serological and molecular detection of HHV-8 in Brazilian populations

Cunha,Andréa Mendonça Gusmão; Costa,Sandra Cecília Botelho; Costa,Fernando Ferreira; Caterino-de-Araújo,Adele; Castro Filho,Bernardo Galvão

Date: 2005   |   Origin: Oasisbr

Accuracy of the serological ELISA test compared with the polymerase chain react...

Parmigiani,Silvana Varella; Barini,Ricardo; Costa,Sandra Cecília Botelho; Amaral,Eliana; Silva,José Carlos Gama da; Pinto e Silva,João Luiz de Carvalho

CONTEXT: The most frequently used methods for detecting antibodies are the indirect immunofluorescence test and the enzymatic immunoassay (ELISA). The polymerase chain reaction is a molecular biology technique in which the production of large amounts of specific DNA fragments is induced from very low concentrations of complex substrates aloowing the detection of very low amounts of viral particles. OBJECTIVE: T...

Date: 2003   |   Origin: Oasisbr

Multiple lymphoid nodules in bone marrow biopsy in immunocompetent patient with...

Magalhães,Silvia Maria Meire; Duarte,Fernando Barros; Vassallo,José; Costa,Sandra Cecília Botelho; Lorand-Metze,Irene

In Brazil, a high prevalence of cytomegalovirus (CMV) infection has been documented. In immunocompetent adults CMV infection is usually asymptomatic and therefore morphologic and immunophenotypic bone marrow changes have rarely been described. The authors report the case of a previously healthy patient who developed fever of undetermined origin. The diagnosis of acute CMV infection was based on serological test...

Date: 2001   |   Origin: Oasisbr

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