6 documents found, page 1 of 1
TASTY trial: protocol for a study on the triad of nutrition, intestinal microbi...
Charneca, Sofia; Hernando, Ana; Almada-Correia, Inês; Polido Pereira, Joaquim; Vieira, Adriana; Sousa, Joana; Almeida, Ana S.; Motta, Carla MottaBackground: The gut microbiota has been implicated in the onset and progression of Rheumatoid Arthritis (RA). It has been proposed that gut dysbiosis impairs gut barrier function, leading to alterations in mucosal integrity and immunity. This disruption allows bacterial translocation, contributing to the perpetuation of the inflammatory process. Since diet is recognised as a key environmental factor influencing...
Beyond seasoning : the role of herbs and spices in rheumatic diseases
Charneca, Sofia; Hernando, Ana; Costa Reis, Patricia; Guerreiro, Catarina SousaAlthough we have witnessed remarkable progress in understanding the biological mechanisms that lead to the development of rheumatic diseases (RDs), remission is still not achieved in a substantial proportion of patients with the available pharmacological treatment. As a consequence, patients are increasingly looking for complementary adjuvant therapies, including dietary interventions. Herbs and spices have a l...
Let’s review the gut microbiota in systemic lupus erythematosus
Almada-Correia, Inês; Costa Reis, Patricia; Guerreiro, Catarina Sousa; Fonseca, João EuricoSystemic lupus erythematosus (SLE) is a chronic, immune-mediated disease associated with significant morbidity and mortality. New evidence suggests that diet, gut microbiota, intestinal permeability, and endotoxemia may modulate chronic inflammation and disease activity in SLE. This review focus on what is known about the gut microbiota in lupus mouse models and SLE patients and the possible mechanisms that con...
The added value of a multidisciplinary clinic for systemic autoinflammatory dis...
Zinterl, Carolina; Costa Reis, Patricia; Esteves, Isabel Castro; Marques, José; Sousa, Ana Berta; Fonseca, João Eurico; Oliveira Ramos, FilipaBackground: Systemic autoinflammatory diseases (SAID) are characterized by inappropriate activation of the innate immune system and include not only monogenic periodic fever syndromes but also multifactorial conditions. As SAID are rare and represent a diagnostic challenge, a multidisciplinary approach is important to ensure successful diagnosis and adequate follow-up of these patients. Objective: To describe t...
Pediatric transplantation in Europe during the COVID‐19 pandemic: Early impact ...
Doná, Daniele; Torres Canizales, Juan; Benetti, Elisa; Cananzi, Mara; De Corti, Federica; Calore, Elisabetta; Hierro, Loreto; Ramos Boluda, EstherThe current pandemic SARS-CoV-2 has required an unusual allocation of resources that can negatively impact chronically ill patients and high-complexity procedures. Across the European Reference Network on Pediatric Transplantation (ERN TransplantChild), we conducted a survey to investigate the impact of the COVID-19 outbreak on pediatric transplant activity and healthcare practices in both solid organ transplan...
Sinus node disfunction in an adolescent with systemic lupus erythematosus
Fogaça Da Mata, Miguel; Rebelo, Mónica; Sousa, Helena Sofia; Rocha, Alexandra; Miguel, Pedro; Oliveira Ramos, Filipa; Costa Reis, PatriciaCardiac involvement in systemic lupus erythematosus (SLE) is well documented. The pericardium, myocardium and endocardium, as well as the coronary arteries, the valves and the conduction system can all be affected. While pericarditis is common, arrythmias are less frequently described.We present a 13-year-old male, who had fatigue, anorexia, weight loss, myalgias and arthralgias for four months. On physical exa...