3 documents found, page 1 of 1
High-yield production of nano-lateral size graphene oxide by high-power ultraso...
Timochenco, L; Costa-Almeida, R; Bogas, D; Silva, FALS; Silva, J; Pereira, A; Magalhães, FD; Pinto, AMNanographene oxide (GOn) constitutes a nanomaterial of high value in the biomedical field. However, large scale production of highly stable aqueous dispersions of GOn is yet to be achieved. In this work, we explored high-power ultrasonication as a method to reduce particle size of GO and characterized the impact of the process on the physicochemical properties of the material. GOn was obtained with lateral dime...
Graphene oxide topical administration: Skin permeability studies
Silva, FALS; Costa-Almeida, R; Timochenco, L; Amaral, SI; Pinto, S; Gonçalves, IC; Fernandes, JR; Magalhães, FD; Sarmento, B; Pinto, AMNanostructured carriers have been widely used in pharmaceutical formulations for der-matological treatment. They offer targeted drug delivery, sustained release, improved biostability, and low toxicity, usually presenting advantages over conventional formulations. Due to its large surface area, small size and photothermal properties, graphene oxide (GO) has the potential to be used for such applications. Nanogr...
Near-infrared radiation-based mild photohyperthermia therapy of non-melanoma sk...
Costa-Almeida, R; Bogas, D; Fernandes, JR; Timochenco, L; Silva, FALS; Meneses, J; Gonçalves, IC; Magalhães, FD; Pinto, AMUsing a one-step thermal reduction and non-covalent chemical functionalization process, PEGylated reduced nanographene oxide (rGOn-PEG) was produced from nanographene oxide (GOn) and characterized in terms of particle size, dispersion stability, chemistry, and photothermal properties, in view of its use for photothermal therapy (PTT) of non-melanoma skin cancer. GOn infrared spectrum presented more intense band...