5 documents found, page 1 of 1
Exploring the transcriptional landscape of phagehost interactions using novel h...
Putzeys, Leena; Wicke, Laura; Brandão, Ana Catarina Ribeiro; Boon, Maarten; Pires, Diana Priscila Penso; Azeredo, Joana; Vogel, Jörg; Lavigne, RobIn the last decade, powerful high-throughput sequencing approaches have emerged to analyse microbial transcriptomes at a global scale. However, to date, applications of these approaches to microbial viruses such as phages remain scarce. Tailoring these techniques to virus-infected bacteria promises to obtain a detailed picture of the underexplored RNA biology and molecular processes during infection. In additio...
Erratum for Oliveira et al., "Functional Analysis and Antivirulence Properties ...
Oliveira, Hugo Alexandre Mendes; Costa, Ana Rita Martins; Ferreira, Alice Maria Fernandes; Konstantinidis, Nico; Santos, Sílvio Roberto BrancoVolume 93, no. 4, e01163-18, 2019, https://doi.org/10.1128/JVI.01163-18. Page 14, Acknowledgments, line 4: (POCI-01-0145-FEDER-016678) should read (POCI-01-0145-FEDER-016643).
API480: features towards therapy in honeybee hives
Ribeiro, Henrique Gonçalves; Melo, Luís Daniel Rodrigues; Oliveira, Hugo Alexandre Mendes; Boon, Maarten; Lavigne, Rob; Azeredo, Joana; Oliveira, A.American foulbrood disease (AFB) is a devastating bacterial disease affecting honeybees. It is caused by Paenibacillus larvae, a worldwide-distributed spore forming Gram-positive bacterium which spread easily across apiaries producing highly resistant spores. When AFB symptoms are found the burning of contaminated hives is mandatory causing serious economic losses [1]. Bacteriophages (phages) are being consider...
Functional analysis and antivirulence properties of a new depolymerase from a m...
Oliveira, Hugo Alexandre Mendes; Costa, Ana Rita Martins; Ferreira, Alice Maria Fernandes; Konstantinides, Nico; Santos, Sílvio Roberto BrancoAcinetobacter baumannii is an important pathogen causative of healthcare-associated infections and is able to rapidly develop resistance to all known antibiotics including colistin. As an alternative therapeutic agent, we have isolated a novel myovirus (vB_AbM_B9) which specifically infects and makes lysis from without in strains of the K45 and K30 capsule type, respectively. Phage B9 has a genome of 93,641 bp ...
Characterization of a new podovirus infecting Paenibacillus larvae
Ribeiro, Henrique G.; Melo, Luís Daniel Rodrigues; Oliveira, Hugo Alexandre Mendes; Boon, Maarten; Lavigne, Rob; Noben, Jean-Paul; Azeredo, JoanaThe Paenibacillus larvae infecting phage API480 (vB_PlaP_API480) is the first reported podovirus for this bacterial species, with an 58nm icosahedral capsid and a 12×8nm short, non-contractile tail. API480 encodes 77 coding sequences (CDSs) on its 45,026bp dsDNA genome, of which 47 were confirmed using mass spectrometry. This phage has got very limited genomic and proteomic similarity to any other known ones re...