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A multicentric analysis of prognostic factors in malignant pleural mesothelioma

Batista, Mafalda; Barata, Juliana; Costa-Martins, Sara; Valente, Maria Jesus; Oliveira Fernandes, Maria Gabriela; Saleiro, Sandra; Souto Moura, Madalena

Background: Malignant pleural mesothelioma is a rare entity with poor prognosis, linked to previous asbestos exposure. The main goal of this study was to analyse the impact of clinical factors on mesothelioma prognosis. Methods: Retrospective cohort study of patients with malignant pleural mesothelioma in three Portuguese institutions, from 1999 to 2020. Statistical analysis was performed with Kaplan–Meier meth...


Two-year treatment with Pembrolizumab monotherapy in advanced non-small cell lu...

Costa-Martins, Sara; Valente, Salete; Pêgo, Alice; Figueiredo, Ana; Barata, Fernando

Introduction and objectives: Immunotherapy has introduced advances in the treatment of non -small cell lung cancer. However, data from current clinical practice on potential responder groups, optimal duration of treatment and safety issues remain unclear. It is intended to produce a reflection on the population of patients with a favourable response to Pembrolizumab and how they have evolved clinically over tim...


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