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Roles of the hox proteins in cancer invasion and metastasis

Paço, A; Garcia, SAB; Leitão-Castro, J; Costa-Pinto, AR; Freitas, R

Invasion and metastasis correspond to the foremost cause of cancer-related death, and the molecular networks behind these two processes are extremely complex and dependent on the intra-and extracellular conditions along with the prime of the premetastatic niche. Currently, several studies suggest an association between the levels of HOX genes expression and cancer cell invasion and metastasis, which favour the ...


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