9 documents found, page 1 of 1

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Continuous production of highly tuned silk/calcium-based composites: exploring ...

Veiga, Anabela; Magalhaes, Rui; Duarte, Marta M.; Dias, Juliana R.; Alves, Nuno M.; Costa-Pinto, Ana Rita; Castro, Filipa; Rocha, Fernando

Calcium plays an important role in barrier function repair and skin homeostasis. In particular, calcium phosphates (CaPs) are well established materials for biomedical engineering due to their biocompatibility. To generate biomaterials with a more complete set of biological properties, previously discarded silk sericin (SS) has been recovered and used as a template to grow CaPs. Crucial characteristics for skin...

Date: 2022   |   Origin: IC-online

Continuous production of highly tuned silk/calcium-based composites: exploring ...

Veiga, Anabela; Magalhães, Rui; Duarte, Marta M.; Dias, Juliana R.; Alves, Nuno M.; Costa-Pinto, Ana Rita; Castro, Filipa; Rocha, Fernando

Calcium plays an important role in barrier function repair and skin homeostasis. In particular, calcium phosphates (CaPs) are well established materials for biomedical engineering due to their biocompatibility. To generate biomaterials with a more complete set of biological properties, previously discarded silk sericin (SS) has been recovered and used as a template to grow CaPs. Crucial characteristics for skin...


Hydrolysates of mytilus galloprovincialis as a source of bioactive compounds

Cunha, Sara; Coscueta, Ezequiel; Nova, Paulo; Costa-Pinto, Ana Rita; Sarmento, Bruno; Pintado, Manuela


In Situ Forming Silk Sericin-Based Hydrogel: A Novel Wound Healing Biomaterial

Baptista-Silva, Sara; Borges, Sandra; Costa-Pinto, Ana Rita; Costa, Raquel; Amorim, Manuela; Dias, Juliana R.; Ramos, Óscar; Alves, Paulo

In situ cross-linked hydrogels have the advantage of effectively fulfilling the wound in its shape and depth. Amongst the new generation of natural-based biopolymers being proposed for wound care and skin regeneration, silk sericin is particularly interesting due to its exceptional properties such as biocompatibility, biodegradability, and antioxidant behavior, among others. In this study, a new enzyme-mediated...

Date: 2021   |   Origin: IC-online

Microalgae as a source of natural ingredients for application in cosmetic industry

Cunha, Sara A.; Costa-Pinto, Ana Rita; Silva, Joana L.; Sarmento, Bruno; Pintado, Manuela


Chitosan and hydroxyapatite based biomaterials to circumvent periprosthetic joi...

Costa-Pinto, Ana Rita; Lemos, Ana Luísa; Tavaria, Freni Kekhasharú; Pintado, Manuela

Every year, worldwide, millions of people suffering from joint pain undergo joint replace-ment. For most patients, joint arthroplasty reduces pain and improve function, though a small fraction will experience implant failure. One of the main reasons includes prosthetic joint infection (PJI), involving the prosthesis and adjacent tissues. Few microorganisms (MO) are required to inocu-late the implant, resulting ...


In situ enabling approaches for tissue regeneration: current challenges and new...

Dias, Juliana R.; Ribeiro, Nilza; Baptista-Silva, Sara; Costa-Pinto, Ana Rita; Alves, Nuno; Oliveira, Ana. L.

In situ tissue regeneration can be defined as the implantation of tissue-specific biomaterials (by itself or in combination with cells and/or biomolecules) at the tissue defect, taking advantage of the surrounding microenvironment as a natural bioreactor. Up to now, the structures used were based on particles or gels. However, with the technological progress, the materials’ manipulation and processing has becom...


Sardine roe as a source of lipids to produce liposomes

Guedes, Marta; Costa-Pinto, Ana Rita; Gonçalves, Virgínia; Moreira-Silva, Joana; Tiritan, Maria; Reis, Rui L.; Ferreira, Helena; Neves, Nuno M.

Sea-derived materials have promising applications in the medical, pharmaceutical, and biotechnological fields. Fish roe, for example, is a highly nutritional product, presenting diverse beneficial effects on human health. Therefore, this work explored extracts of sardine (Sardina pilchardus) roe, due to the well-known health benefits of this fish, to produce novel and promising delivery systems. After morpholog...


Assessment of baby Bibs. GC-MS screening, migration into saliva and insight of ...

Rajbux, Chandisree; Pereira, Joel; Selbourne, Maria do Céu; Costa-Pinto, Ana Rita; Poças, Fátima

Plastic baby Bibs are, according to the European legislation, food contact materials. Therefore, compositional and migration limits applicable to plastics should be observed. This work aimed at identifying potential migrants in Bibs from European market and determining the migration into artificial saliva. Bibs were subjected to screening analyses (GC-MS). Thirty substances non-authorised in European or Swiss l...


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