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VEGF promotes malaria-associated acute lung injury in mice

Epiphanio, Sabrina; Campos, Marta G.; Pamplona, Ana; Carapau, Daniel; Pena, Ana C.; Ataíde, Ricardo; Monteiro, Carla A. A.; Félix, Nuno

The spectrum of the clinical presentation and severity of malaria infections is broad, ranging from uncomplicated febrile illness to severe forms of disease such as cerebral malaria (CM), acute lung injury (ALI), acute respiratory distress syndrome (ARDS), pregnancy-associated malaria (PAM) or severe anemia (SA). Rodent models that mimic human CM, PAM and SA syndromes have been established. Here, we show that D...

Date: 2010 | Origin: Repositório da Universidade de Lisboa

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