2 documents found, page 1 of 1
Association of HMIP1 C-893A polymorphism and disease severity in patients with ...
Pereira-Martins, Diego A.; Domingos, Igor F.; Belini-Junior, Edis [UNESP]; Coelho-Silva, Juan L.; Weinhäuser, Isabel; Araújo, Aderson S.Made available in DSpace on 2020-12-12T02:46:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Introduction: Sickle cell anemia (SCA) is a Mendelian disorder with a heterogeneous clinical course. The reasons for this phenotypic diversity are not entirely established, but it is known that high fetal hemoglobin levels lead to a milder course of the disease. Additionally, genetic variants in the int...
Global analysis of erythroid cells redox status reveals the involvement of Prdx...
Romanello, Karen S.; Teixeira, Karina K.L.; Silva, João Pedro M.O.; Nagamatsu, Sheila T.; Bezerra, Marcos André C.; Domingos, Igor F.Made available in DSpace on 2019-10-06T16:08:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); β-thalassemia is a worldwide distributed monogenic red cell disorder, characterized by an absent or reduced beta globin chain synthesis. The unbalance of alpha-gamma chain and the presence of pathological free iron promote severe oxidative d...