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Comparative effectiveness of anti-IL5 and anti-IgE biologic classes in patients...

Pfeffer, Paul E.; Ali, Nasloon; Murray, Ruth; Ulrik, Charlotte; Tran, Trung N.; Maspero, Jorge; Peters, Matthew; Christoff, George C.

Background: Patients with severe asthma may present with characteristics representing overlapping phenotypes, making them eligible for more than one class of biologic. Our aim was to describe the profile of adult patients with severe asthma eligible for both anti-IgE and anti-IL5/ 5R and to compare the effectiveness of both classes of treatment in real life. Methods: This was a prospective cohort study that inc...


A glimpse of the ERS International Congress 2022

Gompelmann, Daniela; Farr, Amy; Simonds, Anita; Brightling, Christopher; Roche, Nicolas; Laveneziana, Pierantonio; Costello, Richard W.; Meiners, Silke

The European Respiratory Society (ERS) International Congress is an annual event where thousands of experts from around the world come together to present and discuss the latest scientific and clinical advances in the respiratory field. During the pandemic, there was a need to change the format of the Congress from in-person to an online format (2020 and 2021) to limit the exposure to the coronavirus. This year...

Date: 2022   |   Origin: IC-online

Spacers and valved holding chambers : the risk of switching to different chambers

Lavorini, Federico; Barreto, Celeste; van Boven, Job FM; Carroll, Will; Conway, Joy; Costello, Richard W.; Dahl, Birthe Hellqvist

Spacers are pressurized metered-dose inhaler (pMDI) accessory devices developed to reduce problems of poor inhaler technique with pMDIs. Spacers that feature a 1-way inspiratory valve are termed valved holding chambers (VHCs); they act as aerosol reservoirs, allowing the user to actuate the pMDI device and then inhale the medication in a 2-step process that helps users overcome challenges in coordinating pMDI a...


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