3 documents found, page 1 of 1
Characterization of a clone from an adult worm cDNA library selected with anti-...
Valli, Luiz Carlos Pedrosa; Kanamura, Herminia Yohko; Cotrim, Paulo Cesar; Oliveira, Guilherme Correa; Oliveira, Edward José DeMade available in DSpace on 2019-09-11T20:58:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2007; Considerando a escassez de antígenos quimicamente definidos, realmente úteis e confiáveis para aplicação na soroepidemiologia da esquistossomose em larga escala, foi proposto, neste trabalho, um método alternativo para a seleção de clones de cDNA que expressam proteínas com putativo potencial diagnóstico na e...
Targeting Leishmania amazonensis amastigotes through macrophage internalisation...
Monteiro, Lis Marie; Löbenberg, Raimar; Ferreira, Elizabeth Igne; Cotrim, Paulo Cesar; Kanashiro, Edite; Rocha, Mussya; Chung, Man Chin [UNESP]Made available in DSpace on 2018-12-11T17:23:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-07-01; Dextran-coated poly (n-butyl cyanoacrylate) nanoparticles (PBCA-NPs) were prepared and were evaluated for enhanced delivery of a promising anti-Leishmania drug candidate, hydroxymethylnitrofurazone (NFOH), to phagocytic cells. Currently available chemotherapy for leishmaniasis, such as pentavalent antim...
Characterization of a clone from an adult worm cDNA library selected with anti-...
Valli, Luiz Carlos Pedrosa; Kanamura, Herminia Yohko; Cotrim, Paulo Cesar; Oliveira, Guilherme Correa; Oliveira, Edward José deConsidering the scarcity of defined antigens, actually useful and reliable for use in the field studies, we propose an alternative method for selection of cDNA clones with potential use in the diagnosis of schistosomiasis. Human antibodies specific to a protein fraction of 31/32 kDa (Sm31/32), dissociated from immune complexes, are used for screening of clones from an adult worm cDNA library. Partial sequencing...