24 documents found, page 1 of 3
Development of a predictive score to discriminate community acquired pneumonia ...
Barbosa-Martins, João; Mendonça, Joana; Carvalho, Nuno; Carvalho, Carolina; Sarmento, Helena; Soutinho, Gustavo; Coutinho, Camila; Cotter, JorgeBackground: A pneumonic infiltrate might hide an occult lung cancer (LC). This awareness depends on each clinician personal experience, turning definitive LC diagnosis challenging and possibly delayed. In this study we aimed to develop a clinical score to better identify those cases. Materials and Methods: We conducted a retrospective case–control study, including previously undiagnosed LC patients admitted in ...
Exploring the diversity of visceral, subcutaneous and perivascular adipose tiss...
Ferreira, Joana; Afonso, Julieta Alexandra Pereira; Carneiro, Alexandre Lima; Vila, Isabel; Cunha, Cristina; Roque, Susana; Silva, CristinaThe prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to correlate them with cardiovascular risk factors, anthropometric measures and medication. An observational and prospective study was conducted, and 177 subjects w...
The Impact of Biological Drugs in Patients with Rheumatoid Arthritis
Sá, Ana; Freitas, Sara; Alves, Glória; Cotter, JorgeIntroduction: Rheumatoid arthritis (RA) is a disabling autoimmune disease. Biological agents have dramatically altered the natural course of the disease. This study evaluated the impact of these drugs on patients’ lives and analyzed the factors responsible for a better response to treatment.Material and Methods: Retrospective study of 80 patients diagnosed with RA and treated with biological drugs between Janua...
Mononeuropathy multiplex in a Churg-Strauss syndrome patient – case report
Gonçalves, Filipe; Esculcas, Fernando; Cunha, Pedro; Cotter, JorgeA 44 year-old male with asthma and allergic to grass pollen came to our Emergency Department with dyspnea, productive cough, paresthesia, dysaesthesia and dysphonia. He was admitted with a diagnosis of community-acquired pneumonia. An acute axonal polyneuropathy has developed preventing the patient from walking becoming totally dependent on others. In spite of exhaustive investigation the aetiology was not asce...
Is obesity a risk factor for carotid atherosclerotic disease?—opportunistic review
Ferreira, Joana; Cunha, Pedro; Carneiro, Alexandre; Vila, Isabel; Cunha, Cristina; Silva, Cristina; Longatto, Adhemar; Mesquita, Amílcar; Cotter, JorgeObesity is a risk factor for coronary atherosclerosis. However, the influence of adipose tissue in carotid atherosclerosis is not completely understood. No systematic review/meta-analysis was previously performed to understand if obesity is a risk factor for carotid atherosclerosis. This paper aims to provide an opportunistic review of the association between obesity and carotid atherosclerosis and define the r...
Clostridium difficile Severity and Outcome at a North of Portugal Healthcare Fa...
Barbosa-Martins, João; Mendonça, Joana; Carvalho, Carolina; Sarmento, Helena; Mota, Paula; Coutinho, Camila; Cotter, JorgeIntroduction: Clostridium difficile infection has been increasingly reported, with a significant healthcare burden and important morbimortality. This study aimed to characterize and describe the severity and outcomes of this event at a Portuguese hospital.Material and Methods: We conducted a retrospective analysis, by clinical record review, of all confirmed cases diagnosed in a hospital in the North of Portuga...
Reflections on The Internal Medicine Service of Hospital De Guimarães
Cotter, Jorge
Sarcopenia and atherosclerotic occlusive disease: how much we know and what we ...
Ferreira, Joana; Carneiro, Alexandre; Cunha, Pedro; Mansilha, Armando; Vila, Isabel; Cunha, Cidália Cristina Ferreira da; Silva, CristinaPurpose/Background: Sarcopenia (decrease of muscle mass and function) has been linked with atherosclerosis [1]. The EWGSOP2 updated consensus, uses low muscle strength as the primary indicator of sarcopenia [2]. It is acknowledged that strength is better than mass for predicting adverse outcomes [2]. Handgrip strength (HGS) is a simple assessment to estimate overall muscular strength [3]. and is associated with...
THE ROLE OF THE SKELETAL MUSCLE IN ATHEROSCLEROSIS
Ferreira, Joana; Cunha, Pedro; Mansilha, Armando; Cunha, Cristina; Silva, Cristina; Vila, Isabel; Cotter, Jorge; Mesquita, AmílcarThe role of visceral obesity in atherosclerosis is well recognized by the medical community. On the contrary, the importance of skeletal muscle is almost unknown. Muscle is nowadays understood as an endocrine organ producing myokines with direct action in several physiological and pathological pathways, including atherosclerosis. The myokines reduce the formation of neointima, expression of inflammatory mediato...
Comparison of Salt Intake in Children to that of their Parents
Cotter, Jorge; Cotter, Maria J.; Oliveira, Pedro; Cunha, Pedro; Torres, Elisa; Polonia, JorgeHigh salt intake has been related to increased blood pressure and cardiovascular events. Few studies evaluated daily salt consumption in children. Background: High salt intake has been related to increased blood pressure and cardiovascular events. Few studies evaluated daily salt consumption in children. Objective: To compare urinary sodium (UNa) excretion in children to that of their parents using the gold sta...