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Pan-Enteric Capsule Endoscopy: Current Applications and Future Perspectives

Rosa, Bruno; Andrade, Patrícia; Lopes, Sandra; Gonçalves, Ana Rita Marques; Serrazina, Juliana; Marílio Cardoso, Pedro; Silva, Andrea

Background: The role of capsule endoscopy in the evaluation of the small bowel is well established, and current guidelines position it as a first-line test in a variety of clinical scenarios. The advent of double-headed capsules further enabled the endoscopic assessment of colonic mucosa and the opportunity for a one-step noninvasive examination of the entire bowel (pan-enteric capsule endoscopy [PCE]). Summary...


Patient Blood Management – is its application possible in oncology?

Santos, Alexandra; Oliveira, Ana; Raimundo, Ana; Coelho, Andreia; Monteiro, Andreia; Araújo, António; Moreira, António; Nunes, António; Fonseca, Cândida

Patient blood management (PBM) is a safe approach aiming to improve a patient’s medical and surgical management in ways that boost and conserve their own blood. Approximately 32% to 60% of oncology patients have iron deficiency – the majority of whom are anaemic – therefore, it is important to discuss strategies to avoid excessive blood usage and the reduction of tumour progression and cancer recurrence. In thi...


Randomized Controlled Trial for Helicobacter pylori Eradication in a Naive Port...

Boal Carvalho, Pedro; Magalhães, Joana; Dias de Castro, Francisca; Rosa, Bruno; Cotter, José

Introduction: Helicobacter pylori eradication has become increasingly difficult as resistances to several antibiotics develop. We aimed to compare Helicobacter pylori eradication rates between triple therapy and sequential therapy in a naive Portuguese population.Material and Methods: Prospective randomized trial including consecutive patients referred for first-line Helicobacter pylori eradication treatment. E...

Date: 2017   |   Origin: Acta Médica Portuguesa

Endoscopic Scores for Evaluation of Crohn's Disease Activity at Small Bowel Cap...

Rosa, Bruno; Pinho, Rolando; de Ferro, Susana Mão; Almeida, Nuno; Cotter, José; Saraiva, Miguel Mascarenhas

The small bowel is affected in the vast majority of patients with Crohn's Disease (CD). Small bowel capsule endoscopy (SBCE) has a very high sensitivity for the detection of CD-related pathology, including early mucosal lesions and/or those located in the proximal segments of the small bowel, which is a major advantage when compared with other small bowel imaging modalities. The recent guidelines of European So...


Small bowel neuroendocrine tumors: from pathophysiology to clinical approach

Xavier, Sofia; Rosa, Bruno; Cotter, José

Neuroendocrine tumors (NETs), defined as epithelial tumors with predominant neuroendocrine differentiation, are among the most frequent types of small bowel neoplasm. They represent a rare, slow-growing neoplasm with some characteristics common to all forms and others attributable to the organ of origin. The diagnosis of this subgroup of neoplasia is not usually straight-forward for several reasons. Being a rar...


Contrast-enhanced cross sectional imaging and capsule endoscopy: new perspectiv...

Carvalho, Pedro Boal; Cotter, José

Small bowel evaluation is a challenging task and has been revolutionized by high-quality contrasted sectional imaging (CT enterography - CTE) and magnetic resonance enterography (MRE) as well as by small bowel capsule endoscopy (SBCE).The decision of which technique to employ during the investigation of small bowel diseases is not always simple or straightforward. Moreover, contraindications may preclude the us...


Upper gastrointestinal bleeding risk scores: who, when and why?

Monteiro, Sara; Gonçalves, Tiago Cúrdia; Magalhães, Joana; Cotter, José

Upper gastrointestinal bleeding (UGIB) remains a significant cause of hospital admission. In order to stratify patients according to the risk of the complications, such as rebleeding or death, and to predict the need of clinical intervention, several risk scores have been proposed and their use consistently recommended by international guidelines. The use of risk scoring systems in early assessment of patients ...


Multicenter survey on the use of device-assisted enteroscopy in Portugal

Pinho, Rolando; Saraiva, Miguel Mascarenhas; Mão-de-Ferro, Susana; Ferreira, Sara; Almeida, Nuno; Figueiredo, Pedro; Rodrigues, Adélia; Cardoso, Hélder

Background: Device-assisted enteroscopies (DAEs) are recent endoscopic techniques that enable direct endoscopic smallbowel evaluation. Objective: The objective of this article is to evaluate the implementation of DAEs in Portugal and assess the main indications, diagnoses, diagnostic yield, therapeutic yield and complication rate. Methods: We conducted a multicenter retrospective series using a national Web-bas...


Endoscopic scores for evaluation of Crohn’s disease activity at small bowel cap...

Rosa, Bruno; Pinho, Rolando; Mão de Ferro, Susana; Almeida, Nuno; Cotter, José; Saraiva, Miguel Mascarenhas

The small bowel is affected in the vast majority of patients with Crohn's Disease (CD). Small bowel capsule endoscopy (SBCE) has a very high sensitivity for the detection of CD-related pathology, including early mucosal lesions and/or those located in the proximal segments of the small bowel, which is a major advantage when compared with other small bowel imaging modalities. The recent guidelines of European So...


PillCam COLON 2© in Crohn's disease: A new concept of pan-enteric mucosal heali...

Carvalho, Pedro Boal; Rosa, B.; De Castro, F. D.; Moreira, M. J.; Cotter, José

AIM To evaluate mucosal healing in patients with small bowel plus colonic Crohn's disease (CD) with a single non-invasive examination, by using PillCam COLON 2 (PCC2). METHODS Patients with non-stricturing nonpenetrating small bowel plus colonic CD in sustained corticosteroid-free remission were included. At diagnosis, patients had undergone ileocolonoscopy to identify active CD lesions, such as ulcers and eros...


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