2 documents found, page 1 of 1
Successful off-label use of omalizumab in a child with chronic spontaneous urti...
Gonçalves, Tânia; Coutinho, Iolanda Alen; Pita, Joana Sofia; Pinto, Paula LeiriaOmalizumab is approved as third-line therapy for patients older than 12 years with antihistamine-refractory chronic spontaneous urticaria. The authors present the case of an eight-year-old boy with a history of migratory maculopapular skin lesions, arthralgias, and conjunctival hyperemia. Laboratory findings were unremarkable. Skin biopsy was consistent with urticaria. Treatment with oral betamethasone and quad...
Hypersensitivity Reactions to Vaccines: Current Evidence and Standards for SARS...
Carvalho, Jóni Costa; Cunha, Francisca; Coutinho, Iolanda Alen; Loureiro, Carlos; Faria, Emília; Bom, Ana TodoThe first reports of hypersensitivity reactions following the rollout of COVID-19 vaccination programs have raised public concern. Given the recent availability and novel mechanisms of COVID-19 vaccines, there is limited data on possible hypersensitivity reactions. Although it seems rare, the incidence of anaphylaxis for approved COVID-19 vaccines has been suggested as being higher when compared to previous vac...