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PROFILES AND IMPACT OF HYPERTENSIVE DISORDERS IN PREGNANCY: A 10-YEAR RETROSPEC...

Carneiro, Juliana; Coutinho, Joana; Santos, Catarina

Introduction: Hypertensive disorders are one of the main causes of pregnancy-related morbidity and mortality worldwide, and they can be grouped into 4 categories: chronic hypertension, gestational hypertension, pre-eclampsia/eclampsia or pre-eclampsia superimposed on chronic hypertension. Objetive: This study aimed to characterize pregnant women with chronic or gestational hypertension followed in arterial hype...


A Clinical Case of Atypical Hemolytic Uremic Syndrome in Remission: A Step Towa...

Ribeiro, Ligia; Pompermayer, Micael; Coutinho, Joana; Alves Filipe, Rui; Reis Santos, Catarina

Atypical hemolytic uremic syndrome (aHUS) is a rare, complement‑mediated thrombotic microangiopathy requiring early recognition and treatment. We present the case of a 57‑year‑old woman with aHUS triggered by a diarrheal illness, who developed acute kidney injury and hematological abnormalities.Eculizumab was initiated within 48 hours, alongside plasma exchange. The patient achieved hematologic remission within...


Aorthobronchial Fistula: A Rare Cause of Hemoptysis

Forra, Catarina; Grilo, João; Coutinho, Joana; Filipe, Rui

Date: 2025   |   Origin: Gazeta Médica

Frequency of Th1 and Th17 Cells and IL‐17A Levels in Peripheral Blood and Perit...

Grilo, João; Santos, Catarina; Coutinho, Joana; Barreto, Inês; Chorão, Raquel; Filipe, Rui; Monteiro, Andreia; Fonseca, Mafalda; Rocha, Ernesto

Introduction: Chronic kidney disease is characterized by an immune imbalance. In peritoneal dialysis (PD), chronic expo‐ sure to high‐load glucose solutions may further aggravate such disturbances. Among these inflammatory mediators, T helper 1 (Th1) and Th17 cells as well as interleukin 17A (IL‐17A) seem to stand out. We aimed to quantify the frequency of Th1 and Th17 cell subsets and IL‐17A levels in blood an...


Um Caso Desafiante de Doença de Weil

Chambel Belém, Francisco; Grilo, João; Coutinho, Joana; Filipe, Rui; Rocha, Ernesto

A leptospirose é a zoonose mais amplamente disseminada no mundo inteiro. Trata-se de uma doença reemergente, com ampla distribuição geográfica e, em Portugal, apresenta elevada distribuição, sendo uma doença de declaração obrigatória. Devido à inespecificidade dos seus sintomas e sinais iniciais, acaba muitas vezes por ser confundida por outras doenças, no entanto podendo ser de extrema gravidade. Os autores vã...

Date: 2023   |   Origin: SPMI Case Reports

Nodes of the default mode network implicated in the quality of empathic respons...

Oliveira-Silva, Patrícia; Maia, Liliana; Coutinho, Joana; Moreno, Ana Filipa; Penalba, Lucia; Frank, Brandon; Soares, José Miguel; Sampaio, Adriana

The ability to empathize with another person's inner experience is believed to be a central element of our social interactions. Previous research has focused on cognitive (e.g., theory of mind) and emotional (e.g., emotional contagion) empathy, and less on behavioral factors (i.e., the ability to respond empathically). Recent studies suggest that the Default Mode Network (DMN) mediates individual variability in...


When our hearts beat together: cardiac synchrony as an entry point to understan...

Coutinho, Joana; Pereira, Alfredo; Oliveira-Silva, Patrícia; Meier, Deborah; Lourenço, Vladimiro; Tschacher, Wolfgang

The degree to which romantic partners' autonomic responses are coordinated, represented by their pattern of physiological synchrony, seems to capture important aspects of the reciprocal influence and co‐regulation between spouses. In this study, we analyzed couple's cardiac synchrony as measured by heart rate (HR) and heart rate variability (HRV). A sample of 27 couples (N = 54) performed a structured interacti...


Uncovering the bioactivity of Aurantiochytrium sp.: a comparison of extraction ...

Reboleira, João; Félix, Rafael; Vicente, Tânia F. L.; Januário, Adriana P.; Félix, Carina; Melo, Marcelo M.R. de; Silva, Carlos M.; Ribeiro, Ana C.

Aurantiochytrium sp. is an emerging alternative source of polyunsaturated fatty acids (PUFAs), docosahexaenoic acid (DHA), and squalene, playing an important role in the phasing out of traditional fish sources for these compounds. Novel lipid extraction techniques with a focus on sustainability and low environmental footprint are being developed for this organism, but the exploration of other added-value compou...

Date: 2021   |   Origin: IC-online

Evaluating the Potential of the Defatted By-Product of Aurantiochytrium sp. Ind...

Reboleira, João; Félix, Rafael; Félix, Carina; Melo, Marcelo M. R. de; Silva, Carlos M.; Saraiva, Jorge A.; Bandarra, Narcisa M.; Teixeira, Bárbara

While Aurantiochytrium sp. is an increasingly popular source of polyunsaturated fatty acids (PUFAs), its extraction generates high amounts of waste, including the spent, defatted residue. The composition and bioactivities of this by-product could prove to be a major part of the sustainable valorisation of this organism within the framework of a circular economy. In this study, the defatted biomass of commercial...

Date: 2021   |   Origin: IC-online

Psychophysiological synchrony during verbal interaction in romantic relationships

Coutinho, Joana; Oliveira‐Silva, Patrícia; Fernandes, Eugénia; Gonçalves, Oscar F.; Correia, Diogo; Mc‐Govern, Kristin Perrone; Tschacher, Wolfgang

Previous studies about romantic relationships have shown that the reciprocal influence between partners occurs not only at the behavioral and socio‐emotional levels, but also at the psychophysiological level. This reciprocal influence is expressed in a pattern of physiological synchrony between partners (i.e., coordinated dynamics of the physiological time series). The main aim of the present study was to explo...


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