50 documents found, page 1 of 5
Development and Characterization of Thermal Water Gel Comprising Helichrysum it...
Saraiva, Sofia; Crespo, Ana; Vaz, Filipa; Filipe, Melanie; Santos, Daniela; Jacinto, Telma; Paiva-Santos, Ana Cláudia; Rodrigues, MárcioHelichrysum italicum essential oil (H. italicum EO) is recognized for its anti-inflammatory, antimicrobial and wound-healing properties. The main goal of the present work was the development and characterization of a gel formulation comprising H. italicum EO loaded in chitosan nanoparticles (NPs) for dermatological applications. H. italicum EO-loaded chitosan NPs presented hydrodynamic diameter and PdI of about...
Interaction of Near-Infrared (NIR)-Light Responsive Probes with Lipid Membranes...
Filipe, Hugo A. L.; Moreira, André F.; Miguel, Sónia P.; Ribeiro, Maximiano P.; Coutinho, PaulaCancer is considered a major societal challenge for the next decade worldwide. Developing strategies for simultaneous diagnosis and treatment has been considered a promising tool for fighting cancer. For this, the development of nanomaterials incorporating prototypic near-infrared (NIR)-light responsive probes, such as heptamethine cyanines, has been showing very promising results. The heptamethine cyanine-inco...
Thermal spa treatments and benefits perceived by users of Cró and Carvalhal spa...
Pereira, Ana; Fonseca, Cecília; Coutinho, Paula; Cruz, Agostinho; Araujo, André RTSThermalism constitutes one touristic product highly recognized for its enormous potential regarding the exploitation of regional endogenous resources with noteworthy economic impacts for local communities. In the last decades, an important change occurs in the clinical use of thermal water for the treatment of several dermatological diseases, mainly due to the increase of knowledge and research, that highlighti...
Oromucosal Alginate Films with Zein Nanoparticles as a Novel Delivery System fo...
Rodrigues, Daniela A; Miguel, Sónia P; Loureiro, Jorge; Ribeiro, Maximiano; Roque, Fátima; Coutinho, PaulaDigoxin is a hydrophobic drug used for the treatment of heart failure that possesses a narrow therapeutic index, which raises safety concerns for toxicity. This is of utmost relevance in specific populations, such as the elderly. This study aimed to demonstrate the potential of the sodium alginate films as buccal drug delivery system containing zein nanoparticles incorporated with digoxin to reduce the number o...
Operationalisation for Portugal of the EU(7)-PIM List for Identification of Pot...
Rodrigues, Daniel; Herdeiro, Maria; Thürmann, Petra; Figueiras, Adolfo; Coutinho, Paula; Roque, FátimaIntroduction: In 2015, the EU(7)-PIM List was published, which identifies potentially inappropriate medicines in older patients and resulted from a consensus of experts from seven European countries. Portugal was not part of this group, so it was not originally adapted to the Portuguese reality. With this work, we intend to elaborate a list of potentially inappropriate medicines adapted to the reality of medici...
Solvent-Free Microwave Extraction of Thymus mastichina Essential Oil: Influence...
Araujo, André R.T.S.; Périno, Sandrine; Fernandez, Xavier; Cunha, Cassandra; Rodrigues, Márcio; Ribeiro, Maximiano P.; Jordao, Luisa; Silva, Lúcia A.Solvent-free microwave extraction (SFME) is a combination of microwave heating and dry distillation performed at atmospheric pressure without the addition of water or organic solvents that has been proposed as a green method for the extraction of essential oils from aromatic and medicinal herbs. In this work, SFME and the conventional techniques of steam distillation (SD) and hydrodistillation (HD) were compare...
Operationalisation for Portugal of the EU(7)-PIM List for Identification of Pot...
Rodrigues, Daniela A.; Herdeiro, Maria T.; Thürmann, Petra A.; Figueiras, Adolfo; Coutinho, Paula; Roque, FátimaIntroduction: In 2015, the EU(7)-PIM List was published, which identifies potentially inappropriate medicines in older patients and resulted from a consensus of experts from seven European countries. Portugal was not part of this group, so it was not originally adapted to the Portuguese reality. With this work, we intend to elaborate a list of potentially inappropriate medicines adapted to the reality of medici...
Operacionalização para portugal da Lista EU(7)-PIM para identificação de medica...
Rodrigues, Daniela A; Herdeiro, Maria T; Thürmann, Petra A; Figueiras, Adolfo; Coutinho, Paula; Roque, FátimaEm 2015 foi publicada a lista EU(7)-PIM, que identifica medicamentos potencialmente inapropriados na população idosa e resultou de um consenso de peritos de sete países europeus. Portugal não fez parte deste grupo, pelo que na sua origem não foi adaptada para a realidade portuguesa. Com este trabalho pretendemos elaborar uma lista de medicamentos potencialmente inapropriados adaptada à realidade dos medicamento...
Xanthan Gum-Konjac Glucomannan Blend Hydrogel for Wound Healing
Alves, Andreia; Miguel, Sónia P.; Araujo, André R. T. S.; de Jesús Valle, María José; Sánchez Navarro, Amparo; Correia, Ilídio J.; Ribeiro, Maximiano P.Hydrogels are considered to be the most ideal materials for the production of wound dressings since they display a three-dimensional structure that mimics the native extracellular matrix of skin as well as a high-water content, which confers a moist environment at the wound site. Until now, different polymers have been used, alone or blended, for the production of hydrogels aimed for this biomedical application...
Elderly and polypharmacy: physiological and cognitive change
Rodrigues, Daniela A.; Herdeiro, Maria Teresa; Figueiras, Adolfo; Coutinho, Paula; Roque, FátimaPopulation ageing is one of the most significant social transformations of the twenty-first century. The increase in average life expectancy was a successful challenge achieved in the modern world. However, nowadays a new challenge arises for all society: achieving a better quality of life for increasing people’s life. The comorbidities associated with ageing make elderly prone to polypharmacy. On the other han...