163 documents found, page 1 of 17
Understanding the structural and optical evolution of Eu3+ and Dy3+ co-doped YV...
Sekrafi, Houssem Eddine; Hergli, Eya; Ferdov, S.; Coutinho, Paulo J. G.; Rebouta, L.YVO4 nanoparticles co-doped with Eu3+ and Dy3+ ions were successfully synthesized using a conventional coprecipitation method. The resulting phosphors exhibited a single-phase trigonal YVO4 structure, with nanoparticles averaging approximately 60 nm in size, obtained by measurements carried out with scanning electron microscope images. UV–visible diffuse reflectance spectroscopy analysis reveals that the direct...
Multifunctional magneto-plasmonic lipogel based on peptide hydrogel for applica...
Gomes, Valéria; Veloso, Sérgio R. S.; Carvalho, André; Hilliou, L.; Coutinho, Paulo J. G.; Moura, C.; Martins, J. A. R.; Castanheira, Elisabete M. S.Supramolecular hydrogels, particularly low-molecular-weight peptide hydrogels, are promising drug delivery systems due to their ability to change the solubility, targeting, metabolism and toxicity of drugs. Magneto-plasmonic liposomes, in addition to being remotely controllable with the application of an external magnetic field, also increase the efficiency of encapsulated drug release through thermal stimulati...
Potential of photocatalytic nanomaterials for PFOA and PFOS degradation: challe...
Fernandes, Ricardo Jorge Cunha; Silva, Ana Rita Pereira; Cardoso, Beatriz D.; Coutinho, Paulo J. G.; Pereira, LucianaPer- and polyfluoroalkyl substances (PFAS) are persistent chemicals that pose significant environmental and health risks due to their widespread presence in water systems and their accumulation in the human body. Their strong carbon-fluorine bonds provide exceptional structural stability, making them extremely recalcitrant to conventional degradation processes. PFAS exposure has been linked to health issues inc...
New cation sensors based on eugenol-derived azo dyes
Coelho, José R. A.; Pacheco, Ana Rita Faria; Domingues, Diogo C.; Rodrigues, Ana Rita Oliveira; Temitope, Akani A.; Coutinho, Paulo J. G.Eugenol-based azo dyes illustrate how bio-sourced compounds like eugenol can be transformed through synthetic processes into functional and colorful compounds. The main purpose of the present work was to develop new responsive colorimetric sensors for metal cations based on eugenol-derived azo compounds. The incorporation of the azo group into the eugenol framework allows for strong electronic interactions with...
Potential of magnetic silver-coupled zinc and copper ferrite nanoparticles as v...
Fernandes, Ricardo Jorge Cunha; Cardoso, Beatriz D.; Silva, A. R.; Pereira, Luciana; Coutinho, Paulo J. G.Increased environmental concerns about water pollution and scarcity have driven the development of innovative processes and technologies to address these issues. Photocatalysis using nanomaterials is auspicious, with proven efficiency in degrading different pollutants. Ferrite nanoparticles (MFe2O4) stand out for their dual functionality, photocatalytic activity and potential superparamagnetic behavior, that ma...
Novel imidazole-based hydrazonoyl cyanides and amidrazones containing N(N,O)-he...
Fernandes, Soraia P. S.; Gonçalves, Jorge M.; Silva, Bruna F.; Pereira, Eva Q.; Coutinho, Paulo J. G.; Pereira-Wilson, Cristina; Dias, AliceTwo series of novel hybrid heterocyclic compounds that combine the imidazole ring with bioactive piperidine, morpholine or piperazine heterosystems, through a hydrazone unit, were easily obtained by two competitive pathways. Starting from 5-amino-4-cyanoformimidoyl imidazoles and 1-aminopiperidine, 4-aminomorpholine or 1-amino-4-methylpiperazine under mild acidic media led to the selective synthesis of 5-aminoi...
An injectable composite co‐assembled dehydropeptide‐based magnetic/plasmonic li...
Veloso, Sérgio R. S.; Vázquez‐González, Margarita; Spuch, Carlos; Freiría‐Martínez, Luis; Comís‐Tuche, María; Iglesias‐Martínez‐Almeida, MartaAdvancing therapeutic effectiveness through the strategic co-delivery of drugs in a sequential manner represents a compelling strategy. However, achieving precise and selective release of chemotherapeutic agents remains a formidable challenge. In this study, a co-assembled Arginine-Glycine-Aspartate (RGD)-functionalized dehydropeptide-based gel loaded with magnetic liposomes and mesoporous silica-coated gold na...
Highly fluorescent 2-amino-6-cyanopurines as new bioimaging tools for studying ...
Gonçalves, João N. D.; Gonçalves, Jorge M.; Rodrigues, L. R.; Coutinho, Paulo J. G.; Sá, Paulo Correia de; Castanheira, Elisabete M. S.Fluorescent nucleobase analogues (FNAs) have been extensively used for scientific and biomedical purposes owing to their relevant photophysical properties. In this study, five newly synthesized 2-amino-6-cyanopurines were evaluated for their fluorescent probing and imaging capabilities using Saccharomyces cerevisiae as model organism. The new compounds, which were synthesized using highly efficient cost-effecti...
Elastic liposomes containing calcium/magnesium ferrite nanoparticles coupled wi...
Pacheco, Ana Rita Faria; Barros, Ana Margarida; Amorim, Carlos O.; Amaral, Vítor S.; Coutinho, Paulo J. G.; Rodrigues, Ana Rita OliveiraThis work reports on the design, development, and characterization of novel magneto-plasmonic elastic liposomes (MPELs) of DPPC:SP80 (85:15) containing Mg0.75Ca0.25Fe2O4 nanoparticles coupled with gold nanorods, for topical application of photothermal therapy (PTT). Both magnetic and plasmonic components were characterized regarding their structural, morphological, magnetic and photothermal properties. The magn...
Optimization of photoluminescence of Eu<sup>3+</sup> doped YVO<inf>4</inf> nano...
Sekrafi, Houssem Eddine; Hergli, Eya; Ferdov, S.; Mota, André; Lopes, Joni; Coutinho, Paulo J. G.; Rebouta, L.A detailed investigation of the europium-doped yttrium orthovanadate (YVO4:Eu3+) phosphorus prepared by fast and facile microwave synthesis was undertaken. The phase purity, morphology, particle distribution analysis, and photoluminescence were all thoroughly examined. The photoluminescence (PL) properties of the as-synthesized YVO4:Eu3+ nanostructures depend greatly on the synthesis parameters. The PL intensit...