3 documents found, page 1 of 1
The Initial Journey of Patients with Metastatic Pancreatic Cancer (PaCTO Projec...
Barros, AG; Mansinho, H; Couto, N; Teixeira, MR; Tonin, FS; Francisco, R; Duarte-Ramos, FIntroduction: We aimed to characterize the initial healthcare journey of metastatic pancreatic ductal adenocarcinoma (mPDAC) patients in Portugal, including healthcare provision and factors affecting therapeutic decisions, namely BRCA mutations testing. Methods: This is a descriptive cross-sectional, web-based survey using a convenience sampling approach. Portuguese oncologists and pathologists that routinely w...
Absence of KpsM (Slr0977) Impairs the Secretion of Extracellular Polymeric Subs...
Santos, M; Pereira, SB; Flores, C; Príncipe, C; Couto, N; Karunakaran, E; Cravo, SM; Oliveira, P; Tamagnini, PMany cyanobacteria produce extracellular polymeric substances (EPS), composed mainly of heteropolysaccharides, that play a variety of physiological roles, being crucial for cell protection, motility, and biofilm formation. However, due to their complexity, the EPS biosynthetic pathways as well as their assembly and export mechanisms are still far from being fully understood. Here, we show that the absence of a ...
Pancreatic Intraductal Papillary Mucinous Neoplasm Associated Colloid Carcinoma
Flor-de-Lima, B; Freitas, P; Couto, N; Castillo-Martin, M; Santiago, IColloid carcinomas are rare pancreatic tumors characterized by the presence of mucin pools with scarce malignant cells. Most of these neoplasms arise from intestinal-type intraductal papillary mucinous neoplasms (IPMNs). We report a case of a 77-year-old male patient who presented with weight loss, asthenia, lumbar pain and diabetes. Imaging studies revealed a mixed-type IPMN with high-risk features and a possi...