5 documents found, page 1 of 1
On the state-of-the-art of CFD simulations for wave energy converters within th...
Crespo, A; Tagliafierro, B; Martínez-Estévez, I; Domínguez, JM; DeCastro, M; Gómez-Gesteira, M; Altomare, C; Brito, M; Bernardo, F; Ferreira, RM<jats:p>There are currently several types of devices capable of harnessing wave energy, exploiting a broad variety of physical transformation processes. These devices known as Wave Energy Converters (WECs) are developed to maximize their power output. However, there are still uncertainties about their response and survivability to loads induced by adverse environmental conditions, with a consequent increase of ...
Metástase Tiroideia como Manifestação Inicial de um Carcinoma Renal de Células ...
Carmelino, J; Tavares, AP; Crespo, A; Coutinho, JM; Lázaro, A; Ribeiro, V; Barroso, EIntrodução: A metastização para a glândula tiroideia de um carcinoma renal de células claras é rara e só diagnosticável após análise imunohistoquímica de uma amostra histológica. O objetivo deste artigo é reportar um caso de metastização tiroideia como primeira manifestação de um carcinoma renal de células claras. Caso Clínico: Doente do sexo masculino com um nódulo sólido no lobo esquerdo da tiróide, com 5,3 c...
Decrease in APP and CP mRNA expression supports impairment of iron export in Al...
Guerreiro, C; Silva, B; Crespo, A; Marques, L; Costa, S; Timóteo, A; Marcelino, E; Maruta, C; Vilares, A; Matos, M; Couto, F; Faustino, P; Verdelho, AAlzheimer's disease (AD) is a neurodegenerative disorder of still unknown etiology and the leading cause of dementia worldwide. Besides its main neuropathological hallmarks, a dysfunctional homeostasis of transition metals has been reported to play a pivotal role in the pathogenesis of this disease. Dysregulation of iron (Fe) metabolism in AD has been suggested, particularly at the level of cellular iron efflux...
Crosstalk between genetics, gene expression and biochemical markers supports sy...
Crespo, A; Silva, B; Ferreira, C; Marquesa, L; Marcelino, E; Maruta, C; Costa, S; Timóteo, A; Vilares, A; Couto, F; Faustino, P; Correia, AP
Genetic and biochemical markers in patients with Alzheimer's disease support a ...
Crespo, A; Silva, B; Marques, L; Marcelino, E; Maruta, C; Costa, S; Timóteo, A; Vilares, A; Couto, F; Faustino, P; Correia, AP; Verdelho, A; Porto, GAlzheimer's disease (AD) is the most common form of dementia in the elderly individuals, resulting from a complex interaction between environmental and genetic factors. Impaired brain iron homeostasis has been recognized as an important mechanism underlying the pathogenesis of this disease. Nevertheless, the knowledge gathered so far at the systemic level is clearly insufficient. Herein, we used an integrative ...