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Association of enzymatic and optimized ultrasound-assisted aqueous extraction o...
Nicolescu, Alexandru; Babotă, Mihai; Aranda Cañada, Eduardo; Dias, Maria Inês; Añibarro-Ortega, Mikel; Cornea-Cipcigan, Mihaiela; Tanase, CorneliuThe main purpose of the present study was to determine the effect of associating an optimized ultrasound-assisted extraction (UAE) protocol with enzyme-assisted extraction (EAE) in aqueous media, using the dried berries of Hippophae rhamnoides L. (sea buckthorn) as plant material. A specialized software was used for the determination of potential optimal extraction parameters, leading to the development of four...
Optimized ultrasound-assisted extraction of phenolic compounds from Thymus como...
Babotă, Mihai; Frumuzachi, Oleg; Gâvan, Alexandru; Iacoviță, Cristian; Pinela, José; Barros, Lillian; Ferreira, Isabel C.F.R.; Zhang, LeileiAn optimized ultrasound-assisted extractive method was developed to obtain a polyphenol-enriched extract from the aerial parts of Thymus comosus Heuff. ex Griseb. et Schenk. Optimization process was conducted based on Design of Experiment (DoE) principles, determining the influence of three independent variables (time, ultrasound amplitude, ethanol concentration) on the total phenolic content of the extract (de...
Potential therapeutic applications of infusions and hydroalcoholic extracts of ...
Nicolescu, Alexandru; Babotă, Mihai; Ilea, Maria; Dias, Maria Inês; Calhelha, Ricardo C.; Gavrilaș, Laura; Rocchetti, Gabriele; Crişan, GianinaEthnopharmacological relevance: Salvia glutinosa, also known as the glutinous sage, has been used in Romanian folk medicine in the treatment of inflammation, injuries, and mild infections. However, there is no direct scientific evidence to demonstrate these activities. Aim of the Study: The present research was based on evaluating antioxidant, antiproliferative, and α-glucosidase inhibitory activity of S. gluti...
Chemical composition, diuretic, and antityrosinase activity of traditionally us...
Babotă, Mihai; Voştinaru, Oliviu; Păltinean, Ramona; Mihali, Cosmin; Dias, Maria Inês; Barros, Lillian; Ferreira, Isabel C.F.R.; Mocan, AndreiCherry stems (CS) represent a by-product intensively used in Eastern European countries as a traditional remedy for urinary tract disorders. Ethnopharmacological evidences sustain the use of CS as aqueous preparations (infusion and decoction), but few data were previously reported about phytochemical profile and pharmacological potential of CS hydroalcoholic extracts. In this regard, we aimed to evaluate the ph...
Development of an optimized drying process for the recovery of bioactive compou...
Moldovan, Cadmiel; Frumuzachi, Oleg; Babotă, Mihai; Menghini, Luigi; Cesa, Stefania; Gavan, Alexandru; Sisea, Cristian R.; Tanase, CorneliuHot air drying has proven to be an efficient method to preserve specific edible plant materials with medicinal properties. This is a process involving chemical, physical, and biological changes in plant matrices. Understanding these processes will lead to an improvement in the yields of bioactive compounds. This study aims to optimize the drying process of two species’ fruits used in folk medicine, Berberis vul...
Chemical composition and bioactive properties of the wild mushroom: Polyporus s...
Mocan, Andrei; Fernandes, Ângela; Barros, Lillian; Crişan, Gianina; Smiljković, Marija; Soković, Marina; Ferreira, Isabel C.F.R.In Eastern Europe, wild mushrooms are widely collected in mountain areas and used for their medicinal properties or as healthy foods. This study aimed at determining the chemical composition (nutritional value, free sugars, organic acids, phenolic compounds, fatty acids and tocopherols) and bioactive properties (antioxidant, antimicrobial and antiquorum sensing) of wild Polyporus squamosus (Huds.) Fr from Roman...