48 documents found, page 1 of 5
Evaluation of serum levels of C-reactive protein, D-Dimer and Autologous Serum ...
Criado,Roberta Fachini; Bensi,Carolina Games; Criado,Paulo Ricardo; Henriques,Marina Teixeira; de Espindola,Beatriz Alessi RodriguesAbstract Background: The pathophysiology of urticaria is still poorly understood. Recent studies demonstrate that the activation of coagulation is correlated with the clinical activity of Chronic Spontaneous Urticaria. Coagulation and inflammation are strongly linked. Objectives: To correlate the severity and activity of Chronic Spontaneous Urticaria with the levels of D-dimer, C-reactive protein, and autologou...
Socioeconomic impact of high-cost drugs in Brazilian dermatology. Legal and fin...
de Oliveira,Renan Tironi Giglio; Agostinho,Giovana Larissa Prado Leite; Granja,Rubens; Oyafuso,Luiza Keiko M.; Criado,Paulo RicardoAbstract The technological advancement of the pharmaceutical industry, resulting from the techniques of molecular biology and expansion of the knowledge of immunopathogenesis, has modified the therapeutic arsenal used in dermatology. Scientific research and regulatory standards cause drug costs to rise, thus making their use impossible in most public policies. In order to make high-cost drugs viable in the publ...
What lessons can we learn? Clinical and epidemiological retrospective analysis ...
Criado,Roberta Fachini Jardim; Criado,Paulo Ricardo; Baldavira,Nathalia; Cardial,Debora; Gimenez-Arnau,Ana Maria; Machado Filho,Carlos D’ApparecidaAbstract Background: There are few epidemiological studies of urticaria, published in the indexed literature (PubMed/Medline). Objective: The study aimed to evaluate the epidemiological and clinical data among patients with urticaria/angioedema attending a reference clinic in Brazil. Methods: Two hundred sixty-seven patients were evaluated retrospectively considering demographic data, time course of the disease...
A case of tuberculosis verrucosa cutis in Brazil undiagnosed for 15 years
Wedy,Glaucia Ferreira; Passero,Luiz Felipe Domingues; Criado,Paulo Ricardo; Belda Jr.,WalterABSTRACT Tuberculosis verrucosa cutis is a rare medical condition that is caused by the inoculation of Mycobacterium tuberculosis into the skin of a previously sensitized individual. This clinical form of tuberculosis corresponds to 1–2% of all cases of tuberculosis and due to the paucibacillary characteristic of the lesions, patients can be misdiagnosed, accounting for the chronification of the skin infection....
Diagnóstico e terapêutica precoce de vasculite leucocitoclástica: relato de caso
Bezerra,Alexandre Sacchetti; Polimanti,Afonso César; Oliveira,Rafael Andretti de; Fürst,Rafael Vilhena de Carvalho; Criado,Paulo RicardoResumo Paciente do sexo feminino, 46 anos de idade, procurou o pronto socorro do Hospital Municipal Universitário apresentando lesões necróticas em membros inferiores associadas à síndrome consumptiva. Após anamnese e exame físico, obteve-se o diagnóstico de vasculite leucocitoclástica de modo imediato e econômico por meio da utilização de algoritmo específico de vasculites primárias, permitindo início precoce ...
Livedoid Vasculopathy: diagnosis and treatment in pregnant women
Bezerra,Alexandre Sacchetti; Andrade,Accácio de Almeida Abussamra Junqueira de; Polimanti,Afonso César; Fürst,Rafael Vilhena de CarvalhoAbstract Livedoid Vasculopathy is a disease characterized by occlusion of the capillaries of the dermis, without inflammatory signs. It begins with purpuric papules or macules that develop into painful ulcers, mainly involving the ankles and feet. In this case report, we describe diagnosis and treatment in a young pregnant patient, with excellent clinical response.
Is macular lymphocytic arteritis limited to the skin? Long-term follow-up of se...
Morita,Thâmara Cristiane Alves Batista; Trés,Gabriela Franco Sturzeneker; Criado,Paulo RicardoAbstract Background: Macular lymphocytic arteritis most commonly presents as hyperpigmented macules on the lower limbs. The pathogenesis of this disease is still unclear and there is an ongoing debate regarding whether it represents a new form of cutaneous vasculitis or an indolent form of cutaneous polyarteritis nodosa. Objective: To describe clinical, histopathological, and laboratory findings of patients wit...
Update on vasculitis: an overview and dermatological clues for clinical and his...
Morita,Thâmara Cristiane Alves Batista; Trés,Gabriela Franco S.; Criado,Roberta Fachini Jardim; Sotto,Mirian Nacagami; Criado,Paulo RicardoAbstract The term vasculitis refers to the inflammation of vessel walls. It may range in severity from a self-limited disorder in one single organ to a life-threatening disease due to multiple organ failure. It has many causes, although they result in only a few histological patterns of vascular inflammation. Vessels of any type and in any organ can be affected, a fact that results in a broad variety of signs a...
Multinucleate cell angiohistiocytoma: an uncommon cutaneous tumor,
Costa,Anderson Alves; Wedy,Glaucia Ferreira; Belda Junior,Walter; Criado,Paulo RicardoAbstract Multinucleate cell angiohistiocytoma is a rare, benign vascular proliferation of unknown etiology. It occurs mainly in middle-aged women and usually affects the acral regions; the lesions appear as discrete, grouped, and asymptomatic violaceous papules. Histopathology shows proliferation and dilated small vessels in the papillary dermis, fibrous stroma with thickened collagen bundles, and multinucleate...
Update on vasculitis: overview and relevant dermatological aspects for the clin...
Morita,Thâmara Cristiane Alves Batista; Criado,Paulo Ricardo; Criado,Roberta Fachini Jardim; Trés,Gabriela Franco S.; Sotto,Mirian NacagamiAbstract Vasculitis is a group of several clinical conditions in which the main histopathological finding is fibrinoid necrosis in the walls of blood vessels. This article assesses the main dermatological aspects relevant to the clinical and laboratory diagnosis of small- and medium-vessel cutaneous and systemic vasculitis syndromes. The most important aspects of treatment are also discussed.