4 documents found, page 1 of 1
Evaluation of the Cytotoxicity of Ayahuasca Beverages
Simão, Ana Y.; Gonçalves, Joana; Gradillas, Ana; García, Antonia; Restolho, José; Fernández, Nicolás; Rodilla, Jesus M.; Barroso, MárioAyahuasca is a beverage consumed at shamanic ceremonies and currently has gained popularity on recreational scenarios. It contains beta-carboline alkaloids and N,N-dimethyltryptamine, which possesses hallucinogenic effects. Only a few studies have elicited the psychoactive effects and the dose of such compounds on neurological dopaminergic cells or animals. In this work, we aimed to study the cytotoxic effects ...
Supported ionic liquids for the efficient removal of acetylsalicylic acid from ...
Bernardo, Sandra C.; Araújo, Beatriz R.; Sousa, Ana C.A.; Barros, R.; Cristóvão, Ana C.; Neves, Márcia C.; Freire, Mara G.Acetylsalicylic acid, commercially available as aspirin, is one of the most used drugs in the world, being detected in several environmental compartments, including drinking water supplies. Given its environmental impact, the development of a cost‐effective technology capable of removing this pharmaceutical from water samples is of high relevance, for which materials based on silica chemically modified with ion...
Valorization of expired energydrinks by designed and integrated ionic liquid-ba...
Dimitrijević, Aleksandra; Tavares, Ana P. M.; Almeida, Mafalda R.; Vraneš, Milan; Sousa, Ana C. A.; Cristóvão, Ana C.; Trtić-Petrović, TatjanaExpired energy drinks are rich in bioactive value-added compounds that can be recovered and reused in order to valorize food waste within a circular economy perspective. However, to accomplish such requirements, it is necessary to develop sustainable extraction and recovery processes, which must consist of decreasing the number of steps required or developing integrated strategies. In this work, novel aqueous b...
Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse ...
Esteves, Marta; Cristóvão, Ana C.; Saraiva, Tatiana; Rocha, Sandra M.; Baltazar, Graça; Ferreira, L.; Bernardino, LilianaRetinoic acid (RA) plays an important role in the commitment, maturation and survival of neural cells. Recently, RA was pointed as a therapeutic option for some neurodegenerative diseases, including Parkinson's disease (PD). The administration of RA has been defying, and in this sense we have previously developed novel RA-loaded polymeric nanoparticles (RA-NPs) that ensure the efficient intracellular transport ...