37 documents found, page 1 of 4
Overview of clams packaging systems sustainability
Carneiro, A.; Goes, C. B.; Mota, I.; Ferreira, R.; Cruz, A.; Marcos, Begonya; Sivertsvik, M.; Poças, F.Background: This work analyses the protection requirements and options for primary and transportation packaging of shellfish. It considers the properties of materials and the most recent developments and innovations in the arena created by legislation shaping packaging practices and frameworks of circularity and sustainability. A short review of the environmental profiles of typical packaging systems is provide...
Evidence for sporadic Coxiella burnetii excretion in sheep milk, central Portugal
Pires, Humberto; Silva, S. Santos; Cruz, A.; Cardoso, Luís; Lopes, A.P.; Pereira, M.A.; Nóbrega, C.; Mega, A.C.; Santos, C.; Cruz, R.; Esteves, F.Coxiella burnetii, the causative agent of Q fever, is a globally distributed zoonosis, with cattle, sheep, and goats considered the main reservoirs of the disease (Agger et al,., 2013; Bento et al., 2023). Human transmission primarily occurs through inhaling infections aerosols from milk, faeces, urina, and birth products from infected ruminants. This study used a 2-year longitudinal approach to investigate C. ...
Pricing levered warrants under the CEV diffusion model
Glória, C. M.; Dias, J. C.; Cruz, A.Much of the work on the valuation of levered (and unlevered) warrants assumes that the volatility of the underlying state variable is constant. This paper extends the literature on warrant pricing to a more general assumption for the state variable process, the so-called constant elasticity of variance (CEV) process. The CEV model is well-known for its ability to capture some empirical observations found in the...
Collective action in institutional entrepreneuirship: The case of a government ...
Pimentel, L.; Major, M.; Cruz, A.This paper seeks to analyse how and why divergent institutional change occurred in a government agency. While there is evidence of research on the concept of collective action and involvement in the literature on institutional entrepreneurship, the focus has been at the macro and field levels, with scarce attention being given to the topic at the micro and organizational levels. This study addresses this gap in...
Anti-inflammatory effect of the antidepressant fluvoxamine – a systematic review
Ramalho, A.; Carvalho, R.; Barroso, F.; Cruz, A.; Santos, M.Neuroinflammation corresponds to the immune response of the nervous system to an injury, infection or neurodegenerative disease characterized by the activation of resident glial cells, including microglia and astrocytes, the release of cytokines and chemokines and the activation and migration of leukocytes. Evidence suggests that inflammatory cytokines may be a central factor, affecting multiple neuronal pathwa...
The involvement of Nrf2 in depression: systematic review of preclinical studies
Fonseca, D.; Carvalho, R.; Barroso, F.; Cruz, A.; Santos, M.Increased levels of pro-inflammatory cytokines and decreased antioxidant defenses are likely to be linked to the development of depressive symptoms. Nrf2 plays an important role in cellular defense against oxidative stress and binds to ARE, which is located in the promoter region of several phase II antioxidant enzymes and associated stress-responsive enzymes. Reduced Keap1-Nrf2 signaling is implicated in the p...
Role of genetic polymorphisms on neuroplasticity pathways in a cohort of Portug...
Santos, M.; Carvalho, S.; Lima, L.; Mota-Pereira, J.; Pimentel, P.; Correia, D.; Maia, D.; Gomes, S.; Cruz, A.; Medeiros, R.Growing evidence suggests the implication of brain plasticity in antidepressant drug (AD) efficacy. Several authors have been pointing out the role of the BDNF-TrkB signaling pathway, including the downstream kinases Akt and ERK, and the mTOR pathway in neuroplasticity [1-3]. Furthermore, the prediction of AD response phenotypes of depressed patients treated with AD drugs remains a challenge for clinicians. Alt...
Variable-rate mechanical pruning: a new way to prune vines
Botelho, M.; Cruz, A.; Mourato, C.; Castelo-Branco, J.; Ricardo-da-Silva, J.; Ribeiro, H.; Braga, R.Hand pruning is a precise operation, with a visual evaluation of each grapevine to adapt bud load to the vigor. With the advent of mechanical pruning the individual evaluation is lost, and the plant balance relies solely on self-regulation mechanisms. However, precision agriculture provides remote sensing tools for vigor evaluation that allow adapting mechanical pruning to the vine vigor. Variable-rate mechanic...
Complete pathological response (pCR) in gastroesophageal cancer: Correlation wi...
Cabral, Francisco; Cruz, A.; Casaca, R.; Monteiro, C.; Ramos, P.; Pedro, C.; Brandão, F.; Fonseca, R.; Ratão, P.; Saldado, L.; Pinto, Iola; Abecasis, N.Purpose. - Neoadjuvant chemoradiotherapy (nCRT) followed by surgery in patients with resectable esophageal or esophagogastric junctional (GEJ) (Siewert I) cancer is associated with long term overall survival benefits. Up to one third of all patients submitted to nCRT present pathological complete response (pCR). F-18-fluorodeoxyglucose positron emission tomography with CT (F-18-FDG PET-CT) is an important tool ...
Mechanical pruning in non-irrigated vineyards: effects on yield and grape compo...
Botelho, M.; Cruz, A.; Silva, E.B.; Mexia, A.; Ricardo-da-Silva, Jorge M.; Castro, R.; Ribeiro, HenriqueThe effect of mechanical pruning on vine performance and wine quality was evaluated from 2012 until 2015. Two trial fields, with a randomized complete block design, were established on already existing ‘Syrah’ vineyards in Quinta do Côro and Quinta do Gradil, located in Tejo and Lisboa wine regions respectively. Mechanical pruning (MEC) was simulated by trimming all shoots to a 15 cm square around the cordon. M...