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The mechanism of action of pepR, a viral-derived peptide, against Staphylococcu...
Pinto, Sandra; Dias, Susana; Cruz, Ana F; Mil-Homens, Dalila; Fernandes, Fabio; Valle, Javier; Andreu, David; Prieto, Manuel; Castanho, Miguel A. R. B.Objectives: To investigate the mechanism of action at the molecular level of pepR, a multifunctional peptide derived from the Dengue virus capsid protein, against Staphylococcus aureus biofilms. Methods: Biofilm mass, metabolic activity and viability were quantified using conventional microbiology techniques, while fluorescence imaging methods, including a real-time calcein release assay, were employed to inves...
Date: 2019
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Origin: Repositório da Universidade de Lisboa