14 documents found, page 1 of 2
Antipsychotic Polypharmacy and High Doses in a Rural Portuguese Community Menta...
Ramos, Sara; Cruz, Diana; Jesus, Bianca; Correia, João; Vaz, Isabel; Mendes, JoãoIntroduction: Antipsychotic polypharmacy (APP) and high dose (APHD) remain a common practice in the treatment of severe mental illness, even though they are not supported by current international guidelines. Methods: We aimed to establish the prescribing patterns of antipsychotics in a community mental health service in a rural setting, to determine the prevalence of APP and APHD treatment and to identify assoc...
Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte g...
Dias Da Costa, Mariana; Leal Rato, Miguel; Cruz, Diana; Valadas, Anabela; Antunes, Ana Patrícia; Albuquerque, LuísaWe report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection. MRI documented a longitudinally extensive transverse myelitis and further investigation was unremarkable with the exception of positivity for MOG-IgG in serum. This report extends the spectrum of post-COVID-19 neurological syndromes, and documents a very significant improvement to long-term oral corticosteroid ther...
Adolescents’ maps about well-being, distress and selfdestructive trajectories: ...
Cruz, Diana; Narciso, Isabel; Sampaio, DanielThe mapping of adaptive and maladaptive trajectories in adolescence has been a key concern of developmental psychopathology research. Given the importance of studying adolescents’ own expert views of their experiences, we explored the factors that contribute to the adoption of trajectories characterized by well-being, by distress, and self-destructive trajectories, in a convenience sample of 33 community adoles...
Microwave-assisted extraction in goji berries: effect on composition and bioact...
Carvalho, Ana P.; Mendes, Marta; Moreira, Manuela M.; Cruz, Diana; Magalhães, Júlia M. C. S.; Barroso, M. Fátima; Ramalhosa, Maria João; Duarte, AbelThis study aimed to evaluate the effect of microwave-assisted extraction (MAE) parameters on the composition and bioactivity of goji (Lycium barbarum) extracts. Extracts were obtained under a central composite design combination of experimental conditions, and characterised through HPLC-DAD; their bioactive capacity was ascertained for antimicrobial and antioxidant capacity, the later by spectrophotometric [2,2...
DNA-based sensor against nitrite oxide radical: Evaluation of total antioxidant...
Cruz, Diana; Barroso, M. Fátima; Ramalhosa, Maria João; Coelho, Andreia; Silva, Hélder da; Duarte, Abel J.; González-García, Maria BegoñaReactive nitrogen and oxygen species are produced in cells and play an important role in the oxidative metabolism; when in abnormal concentrations, they are able to induce oxidative damage on biomolecules, namely in DNA. In this paper it is described, an electrochemical DNA-based sensor against NOradical dot radical developed for total antioxidant capacity (TAC) evaluation. The sensor consisted on dA20 (adenine...
Microwave-assisted extraction in goji berries: effect on composition and bioact...
Carvalho, Ana P.; Mendes, Marta; Moreira, Manuela M.; Cruz, Diana; Magalhães, Júlia M. C. S.; Barroso, M. Fátima; Ramalhosa, M. J.; Duarte, AbelThis study aimed to evaluate the effect of microwave-assisted extraction (MAE) parameters on the composition and bioactivity of goji (Lycium barbarum) extracts. Extracts were obtained under a central composite design combination of experimental conditions, and characterised through HPLC-DAD; their bioactive capacity was ascertained for antimicrobial and antioxidant capacity, the later by spectrophotometric [2,2...
Adaptation and Psychometric Proprieties Study for the Portuguese Version of the...
Guerreiro, Diogo Frasquilho; Cruz, Diana; Figueira, Maria Luísa; Sampaio, DanielIntroduction: Coping is a psychological process that prompts the individual to adapt to stressful situations. The Adolescent Coping Scale is a widely used research and clinical tool. This study aimed to develop a Portuguese version of the Adolescent Coping Scale and to analyze the strategies and coping styles of young people in our sample.Material and Methods: An anonymous questionnaire comprising the Adolescen...
Self-Destructive Symptomatic Frames in Clinical Adolescents: Is the Same Differ...
Cruz, Diana; Narciso, Isabel; Pereira, Cícero Roberto; Sampaio, DanielThis study examines individual and family predictors of different self-destructive patterns—only suicidal ideation, only nonsuicidal self-injury (NSSI), or suicide attempts (that may also include both suicide ideation (SI) and NSSI)—in a sample of outpatient adolescents (N = 42; 86% females) with mean age of 16 years (SD = 1.86). Results indicated that there are differences in youngsters with self-destructive b...
Risk Trajectories of Self-Destructiveness in Adolescence: Family Core Influences
Cruz, Diana; Narciso, Isabel; Pereira, Cícero Roberto; Sampaio, DanielThe study of family factors, (namely, parenting, attachment and family functioning) that can either reduce or increase risk factors during adolescent development is crucial to the early identification of adolescents at risk for self-destructive thoughts and behaviors (SDTB). Altough several studies have highlighted the role of family factors, few have analysed the joint impact of parenting styles and attachment...
Association Between Deliberate Self-Harm and Coping in Adolescents: A Critical ...
Guerreiro, Diogo; Cruz, Diana; Frasquilho, Diana; Santos, José Carlos Pereira dos; Figueira, Luisa; Sampaio, DanielCoping is commonly associated with deliberate self-harm (DSH) in adolescents. This article reviews the published literature from 2000 to 2010, aiming to highlight the current evidence supporting this association. Eighteen studies met the inclusion criteria, a total sample of 24,702 subjects was obtained and 17% were DSH cases. Emotion-focused coping style and in particular avoidant coping strategies have consis...