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Heterologous expression, purification and crystallization of the human mitochon...

Violante, S; Gaspar, MM; Cruz, MEM; Gomes, C; Carvalho, AL; Romão, MJ; Wanders, RJA; Soveral, G; Leandro, P; Tavares de Almeida, I; Ventura, FV


Strategy for the Characterization of a Human Membrane Membrane Protein

Ventura, FV; Violante, S; Gaspar, MM; Carvalho, AL; Cruz, MEM; Romão, MJ; Soveral, G; Wanders, RJA; Leandro, P; Tavares de Almeida, I


Optimization of bacterial overexpression of human carnitine acylcarnitine trans...

Ventura, F; Violante, S; Jorge, AM; Gaspar, MM; Cruz, MEM; Soveral, G; Leandro, P; Tavares de Almeida, I


Heterologous expression of the human carnitine acylcarnitine translocase (CACT)

Ventura, FV; Violante, S; Jorge, AM; IJlst, L; Gaspar, MM; van Roermund, CWT; Cruz, MEM; Soveral, G; Wanders, RJA; Leandro, P; Tavares de Almeida, I


Developments in the rat adjuvant arthritis model and its use in therapeutic eva...

Simoes, SI; Delgado, TC; Lopes, RM; Jesus, S; Ferreira, AA; Morais, JA; Cruz, MEM; Corvo, ML; Martins, MBF

The aim of this study was firstly to refine a rat model of arthritis, the adjuvant arthritis (AA) model, by studying the time course of the disease, introducing new evaluation methods such as haematological and biochemical parameters in order to identify the main stages of the disease. An optimisation of treatment schedule and evaluation criteria was developed. This refinement provided novel non-invasive anti-i...


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