2 documents found, page 1 of 1
UREMIC CALCIPHYLAXIS UNDER THE CALCIMIMETIC CINACALCET
Ramos, Leonor; Coutinho, I.; Linhares, L.; Brites, M. M.; Cardoso, José Carlos; Tellechea, Óscar; Gonçalo, MargaridaUremic calciphylaxis is a rare but serious complication of dialysis patients. Its pathogenesis is not completely understood, although many risk factors have been identified, such as hyperparathyroidism. Cinacalcet (a calcimimetic agent) is used to keep calcium, phosphorus and PTH within the normal range. A 72-year old female patient, under hemodialysis for 15 years with hyperphosphatemia, normocalcemia and hype...
DR(E)SS TO ABACAVIR CONFIRMED BY PATCH TESTS
Ramos, Leonor; Brites, M. M.; Oliveira, J.; Gonçalo, MargaridaAbacavir hypersensitivity is a potentially fatal systemic adverse reaction that occurs in 2-9% of exposed patients. Symptoms appear during the first 6 weeks of therapy and are similar to DRESS although usually there is no eosinophilia. Studies have confirmed a positive relation with HLA-B*5701, particularly when only cases confirmed by a positive epicutaneous patch test were considered. This HLA allele is now c...