3 documents found, page 1 of 1
Characteristics of healthy vascular ageing in pooled population-based cohort st...
Nilsson, Peter M.; Laurent, Stephane; Cunha, Pedro Miguel Guimarães Marques; Olsen, Michael H.; Rietzschel, Ernst; Franco, Oscar H.; Ryliškytė, LigitaArterial ageing is characterized by increasing arterial stiffness as measured by pulse wave velocity (PWV). This process is enhanced in participants with early vascular ageing (EVA), but slowed in participants with healthy vascular ageing (HVA). We aimed to describe characteristics of EVA and HVA in a transcontinental study including 11 cohorts.
Mitogenome diversity in Sardinians: a genetic window onto an island's past
Olivieri, Anna; Sidore, Carlo; Achilli, Alessandro; Angius, Andrea; Posth, Cosimo; Furtwängler, Anja; Brandini, Stefania; Capodiferro, Marco RosarioSardinians are "outliers" in the European genetic landscape and, according to paleogenomic nuclear data, the closest to early European Neolithic farmers. To learn more about their genetic ancestry, we analyzed 3,491 modern and 21 ancient mitogenomes from Sardinia. We observed that 78.4% of modern mitogenomes cluster into 89 haplogroups that most likely arose in situ. For each Sardinian-specific haplogroup (SSH)...
Arterial stiffness and influences of the metabolic syndrome: a cross-countries ...
Scuteri, Angelo; Cunha, Pedro Guimarães; Rosei, E. Agabiti; Bekaert, Sofie; Cockcrofti, John R.; Cotter, Jorge; Cucca, Francesco; De Buyzere, Marc L.Specific clusters of metabolic syndrome (MetS) components impact differentially on arterial stiffness, indexed as pulse wave velocity (PWV). Of note, in several population-based studies participating in the MARE (Metabolic syndrome and Arteries REsearch) Consortium the occurrence of specific clusters of MetS differed markedly across Europe and the US. The aim of the present study was to investigate whether spec...