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Establishment of a brain cell line (FuB-1) from mummichog (Fundulus heteroclitu...

Ruiz-Palacios, María; Almeida, Mónica; Martins, Manuel A.; Oliveira, Miguel; Esteban, María Ángeles; Cuesta, Alberto

The marine fish mummichog (Fundulus heteroclitus), extensively used as research model, including in ecotoxicology, for over a century has been surpassed by other fish species. This fact may be associated with the lack of cell lines from this species, excellent models for the comprehension of fish physiology, immunology, toxicology and virology, that contribute to the reduction in the number of animals used in r...


Insights on ecotoxicological effects of microplastics in marine ecosystems: the...

Regoli, Francesco; Albentosa, Marina; Avio, Carlo Giacomo; Batel, Annika; Bebianno, Maria; Begout, Marie-Laure; Beiras, Ricardo; Bellas, Juan


Polystyrene nanoplastics alter the cytotoxicity of human pharmaceuticals on mar...

Almeida, Mónica; Martins, Manuel A.; Soares, Amadeu M. V.; Cuesta, Alberto; Oliveira, Miguel

There is an increasing concern on the consequences of the presence of micro(nano)plastics to marine organisms. The present study aimed to provide information on the effects of polystyrene nanoplastics (PSNPs) to fish cells alone and combined with human pharmaceuticals, other emerging contaminants, using as biological models marine fish cell lines SAF-1 and DLB-1. Cells were exposed for 24 h to 100 nm PSNPs, sta...


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