8 documents found, page 1 of 1
Rotavirus alphagastroenteritidis
Vita, Dikudila G.; Santiso-Bellón, Cristina; Lemos, Manuel; Neto, Zoraima; Fortes-Gabriel, Elsa; Brito, Miguel; Sebastião, Cruz S.Funding Information: This research was funded by Abbott Rapid Diagnostics Group, the National Health Research Institute (INIS), Luanda, Angola, the Centro de Investigac & atilde;o em Saude de Angola (CISA), Angola, and the Gulbenkian Foundation, Lisbon, Portugal. The study sponsors had no role in the design of this study. Publisher Copyright: © 2025 by the authors.; Rotavirus alphagastroenteritidis (R. alphagas...
High Detection Rate of Rotavirus Infection Among Children Admitted with Acute G...
Vita, Dikudila; Lemos, Manuel; Neto, Zoraima; Evans, Mathebula; Francisco, Ngiambudulu M.; Fortes, Filomeno; Fernandes, Ema; Cunha, CelsoFunding Information: This research was funded by Abbott Rapid Diagnostics Group. The study sponsors had no role in the design of the study. Publisher Copyright: © 2024 by the authors.; Rotavirus group A (RVA) is a major cause of pediatric acute gastroenteritis (AGE). Vaccination is an effective public health strategy and Angola implemented it in 2014. This hospital-based study aimed to estimate the prevalence o...
Genomic analysis of DS-1-like human rotavirus A strains uncovers genetic relate...
Manjate, Filomena; João, Eva D.; Mwangi, Peter; Chirinda, Percina; Mogotsi, Milton; Garrine, Marcelino; Messa, Augusto; Vubil, Delfino; Nobela, Nélio0.870\u2009\u2212\u200915 SC; The United States Agency for International Development (USAID), grant number AID-656-F-16-00002 and Fundo Nacional de Investiga\u00E7\u00E3o (FNI), Mo\u00E7ambique, grant number 245-INV funded the implementation of the surveillance of rotavirus and other enteropathogens in children less than 5 years of age in Manhi\u00E7a. The whole genome characterization undertaken in this study ...
Genomic characterization of the rotavirus G3P[8] strain in vaccinated children,...
Manjate, Filomena; João, Eva D.; Mwangi, Peter; Chirinda, Percina; Mogotsi, Milton; Messa, Augusto; Garrine, Marcelino; Vubil, Delfino; Nobela, Nélio870–15 SC; the United States Agency for International Development (USAID), grant number AID-656-F-16-00002 and Fundo Nacional de Investigação (FNI), Moçambique, grant number 245-INV, funded the surveillance of rotavirus and other enteropathogens in children less than 5 years of age in Manhiça, in the context of the implementation of the diarrhoeal disease surveillance platform. The Child Health and Mortality Pr...
Molecular Epidemiology of Rotavirus Strains in Symptomatic and Asymptomatic Chi...
Manjate, Filomena; João, Eva D.; Chirinda, Percina; Garrine, Marcelino; Vubil, Delfino; Nobela, Nélio; Kotloff, Karen; Nataro, James P...870-15 SC; the United States Agency for International Development (USAID), grant number AID-656-F-16-00002 and Fundo Nacional de Investiga??o (FNI), Mo?ambique, grant number 245-INV, within the context of diarrhoeal disease surveillance platform implementation. F.M PhD is supported by Calouste Gulbenkian Foundation, grant number 234066. The authors convey many thanks to all the caregivers who consented to the...
Drug Repurposing for COVID-19
Rodrigues, Liliana; Cunha, Renata Bento; Vassilevskaia, Tatiana; Viveiros, Miguel; Cunha, CelsoFunding Information: This work was supported by Funda??o para a Ci?ncia e a Tecnologia (FCT) ?Apoio Especial RESEARCH4COVID-19 project no 434?. Funding Information: Funding: This work was supported by Fundação para a Ciência e a Tecnologia (FCT) “Apoio Especial RESEARCH4COVID-19 project no 434”. Publisher Copyright: © 2022, MDPI. All rights reserved.; In December 2019, the novel severe acute respiratory syndrom...
Structural and nucleic acid binding properties of hepatitis delta virus small a...
Alves, Carolina; Cheng, Hong; Tavanez, João Paulo; Casaca, Ana; Gudima, Severin; Roder, Heinrich; Cunha, CelsoAIM: To further characterize the structure and nucleic acid binding properties of the 195 amino acid small delta antigen, S-HDAg, a study was made of a truncated form of S-HDAg, comprising amino acids 61-195 (∆60HDAg), thus lacking the domain considered necessary for dimerization and higher order multimerization. METHODS: Circular dichroism, and nuclear magnetic resonance experiments were used to assess the str...
Hepatitis delta virus
Cunha, Celso; Tavanez, João P; Gudima, Severin O.Hepatitis delta virus (HDV) is the etiologic agent of the most severe form of virus hepatitis in humans. Sharing some structural and functional properties with plant viroids, the HDV RNA contains a single open reading frame coding for the only virus protein, the Delta antigen. A number of unique features, including ribozyme activity, RNA editing, rolling-circle RNA replication, and redirection for a RNA templat...