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Influence of external bacterial structures on the efficiency of photodynamic in...

Pereira, M. A.; Faustino, M. A. F.; Tomé, J. P. C.; Neves, M. G. P. M. S.; Tomé, A. C.; Cavaleiro, J. A. S.; Cunha, Â.; Almeida, A.

The main targets of photodynamic inactivation (PDI) are the external bacterial structures, cytoplasmic membrane and cell wall. In this work it was evaluated how the external bacterial structures influence the PDI efficiency. To reach this objective 8 bacteria with distinct external structures were selected; 4 Gram-negative bacteria (Escherichia coli, with typical Gram-negative external structures; Aeromonas sal...


Phage therapy to control multidrug-resistant Pseudomonas aeruginosa skin infect...

Vieira, A.; Silva, Y. J.; Cunha, Â.; Gomes, N. C. M.; Ackermann, H-W; Almeida, A.

The main goal of this study was to evaluate the efficiency of phage therapy against one of the most common multidrug-resistant (MDR) agents of skin infections, Pseudomonas aeruginosa. A phage suspension [10(8) plaque-forming units (PFU) mL(-1)] was obtained using the clinical strain P. aeruginosa 709 as the host. The ability of the phage to inactivate P. aeruginosa was evaluated in vitro and ex vivo (human skin...


Conteúdo em flavonóides e fenóis totais e actividade antioxidante de extractos ...

Melo, M. N.; Costa, D. D.; Santos, M. C.; Oliveira, V.; Saraiva, J. A.; Cunha, Â.; Almeida, A.

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