5 documents found, page 1 of 1
A glycolytic phenotype is associated with prostate cancer progression and aggre...
Pertega-Gomes, Nelma; Felisbino, Sergio; Massie, Charlie; Vizcaíno, José R.; Coelho, Ricardo; Sandi, Chiranjeevi; Sousa, Susana SimõesMetabolic adaptation is considered an emerging hallmark of cancer, whereby cancer cells exhibit high rates of glucose consumption with consequent lactate production. To ensure rapid efflux of lactate, most cancer cells express high levels of monocarboxylate transporters (MCTs), which therefore may constitute suitable therapeutic targets. The impact of MCT inhibition, along with the clinical impact of altered ce...
A glycolytic phenotype is associated with prostate cancer progression and aggre...
Pertega-Gomes, Nelma; Felisbino, Sergio [UNESP]; Massie, Charlie E.; Vizcaino, Jose R.; Coelho, Ricardo; Sandi, Chiranjeevi; Simões-Sousa, SusanaMade available in DSpace on 2015-12-07T15:32:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2015. Added 1 bitstream(s) on 2015-12-07T15:52:23Z : No. of bitstreams: 1 PMC4528232.pdf: 4222694 bytes, checksum: a848318dcb332a858ceab0bbd9b0f0a7 (MD5); Foundation for Science and Technology (FCT); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Metabolic adaptation is considered an emerging hallma...
Vacuolar cells seem to be a special trait of the esophagus and crop of carnivor...
Cunha, Alexandre Lobo da; Oliveira, E.; Alves, A.; Guimarães, Fernanda; Calado, Gonçalo
Vacuolar cells seem to be a special trait of the esophagus and crop of carnivor...
Cunha, Alexandre Lobo da; Oliveira, E.; Alves, A.; Guimarães, Fernanda; Calado, Gonçalo
Modulation of poly-N-acetylglucosamine accumulation within mature Staphylococcu...
Cerca, Filipe; França, Ângela; Guimarães, Rodrigo; Hinzmann, Mariana; Cerca, Nuno; Cunha, Alexandre Lobo da; Azeredo, Joana; Vilanova, ManuelPNAG is a major component of Staphylococcus epidermidis biofilms involved in intercellular adhesion as well as in the interaction of the biofilm with components of the host immune response. Synthesis of PNAG has been found to be regulated by several environmental factors. In the present study, the effect of glucose metabolism-dependent culture medium acidification in PNAG accumulation was evaluated. Established...